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TranscriptomicsChromatin immunoprecipitation genome wide location analysis of yeast transcriptional regulators under multiple growth conditions
Genomic binding of 203 transcriptional regulatory proteins under various conditions. Hybridizations of fluorescently-labelled immunoprecipitated vs. whole-cell extract samples on S. cerevisiae intergenic arrays.
ORGANISM(S): Saccharomyces cerevisiae 
2004-09-02 | E-WMIT-10 | biostudies-arrayexpress
Transcriptomics24 Hour Response of M. tuberculosis Erdman TMCC 107 to 20 micromolar clofazimine
3 sets of CFZ-exposed bacteria were compared to 3 sets of bacteria treated with vehicle (DMSO) for 24 hours in an aerated drug killing model.
ORGANISM(S): Mycobacterium tuberculosis 
2020-07-22 | E-MTAB-9350 | biostudies-arrayexpress
ProteomicsA MYCN-independent mechanism mediating secretome reprogramming and metastasis in MYCN-amplified neuroblastoma
MYCN amplification (MNA) is a defining feature of high-risk neuroblastoma (NB) that predicts poor prognosis. However, whether genes within or in close proximity to the MYCN amplicon also contribute to aggressiveness in MNA+ NB remains poorly understood. Here we identify that GREB1, a transcription f...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD039410 | Pride
Mycn Greb1 Myo1b Neuroblastoma Secretome 
TranscriptomicsmiRNA signature for cis-platinum resistant ovarian cancer cells A2780
We have done the analysis of cis-platinum susceptible and resistant ovarian cancer cell lines (A2780). After having passed sample QC on the Bioanalyser2100 and RNA measurement on the Nanodrop instrument, the samples were
labelled using the miRCURYM-^Y Hy3M-^Y/Hy5M-^Y power labeling kit and hybrid...
ORGANISM(S): Homo sapiens 
2011-04-15 | E-MEXP-3141 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse fetus exposed to lung and liver of Perfluorooctane sulfonate (PFOS)
Most of the transcriptional changes induced by PFOS in the fetal mouse liver and lung were related to activation of PPARalpha. When compared to the transcript profiles induced by PFOA (Pubmed ID 17681415), few remarkable differences were found other than up-regulation of Cyp3a genes. Because PFOS ...
ORGANISM(S): Mus musculus 
2009-05-16 | E-GEOD-13302 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse macrophage responses to all-trans retinoic acid between wild type and NCoR-/- mice
Comparison of mouse macrophage responses to all-trans retinoic acid between wild-type and NCoR-/- mice.
ORGANISM(S): Mus musculus 
2006-11-06 | E-MEXP-37 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse macrophage responses to lipopolysaccharide (LPS) and 12-o-tetradecanoylphorbol-13-acetate (TPA) in wild type and NcoR-/- mice
Comparison of mouse macrophage responses to lipopolysaccharide (LPS) and 12-o-tetradecanoylphorbol-13-acetate (TPA) between wild-type and NcoR-/- mice.
ORGANISM(S): Mus musculus 
2006-11-06 | E-MEXP-38 | biostudies-arrayexpress
TranscriptomicsA global network of transcription factors, involving E2A, EBF1 and FOXO1, that orchestrates the B cell fate
It is now established that the transcription factors E2A, EBF1 and FoxoM-BM- 1 play critical roles in B cell development. Here we show that E2A and EBF1 bound regulatory elements present in the Foxo1 locus. E2A and EBF1 as well as E2A and Foxo1, in turn, were wired together by a vast spectrum of cis...
ORGANISM(S): Mus musculus 
2010-06-12 | E-GEOD-21978 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of transcription factor binding in yeast cells perturbed with methyl-methanesulfonate
Genome-wide promoter-binding analysis of transcription factors in S.cerevisiae cells perturbed with 0.03% methyl-methanesulfonate for 60 minutes
ORGANISM(S): Saccharomyces cerevisiae 
2006-05-19 | E-TABM-92 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse macrophage responses to 12-o-tetradecanoylphorbol-13-acetate (TPA), lipopolysaccharide (LPS), and LPS plus dexamethasone between wild type and NCoR-/- mice
Comparison of mouse macrophage responses to 12-o-tetradecanoylphorbol-13-acetate (TPA), lipopolysaccharide (LPS), and LPS plus dexamethasone between wild-type and NCoR-/- mice.
ORGANISM(S): Mus musculus 
2004-08-01 | E-MEXP-39 | biostudies-arrayexpress
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