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ProteomicsChemical crosslinking and mass spectrometry of the human Rix1 complex
PELP1 is a scaffold protein with diverse cellular functions including its role as the central scaffold for the human Rix1 complex (PELP1, WDR18, TEX10, and SENP3). We have reconstituted the mammalian Rix1 complex and identified a sub-complex made of the conserved Rix1 domain of PELP1 and the WDR18 p...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037729 | Pride
Q-exactive Lc-ms Rix1 Protein prospector Pelp1 Bs3 Crosslinking 
ProteomicsProteins associated with RORalpha binding element on SULT1E1 gene
Estrogen sulfotransferase (SULT1E1) metabolically inactivates estrogen and SULT1E1 expression is tightly regulated by multiple nuclear receptors in cells. A series of biochemical techniques have clearly demonstrated that nuclear receptors HNF4alpha and phosphorylated RORalpha at Ser100 form as compl...
ORGANISM(S): Homo sapiens (Human) 
2020-08-26 | PXD016385 | Pride
Ap-ms Sult1e1 gene Lc-msms Roralpha binding element 
TranscriptomicsEffects of pulp and paper mill effluents on gene expression in the fathead minnow hypothalamus
We evaluated the possible mechanisms by which exposures to pulp and paper mill effluents gene expression in the fathead minnow hypothalamus Keywords: Toxicology Sexually mature fathead minnows were exposed to 100% pulp and paper mill effluents for 5 days. Tanks contained 4 females and 2 males. A ...
ORGANISM(S): Pimephales promelas 
2010-07-07 | E-GEOD-17130 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of in vitro derived induced and natural FOXP3+ regulatory T cells and ex-iTreg cells in the mouse
Induced Treg (iTreg) cells are essential for tolerance and can be used therapeutically, yet their stability in vivo and mechanisms of suppression are unresolved. Here, we used a treatment model of colitis to examine the role of autologous IL-10 in iTreg cell function. Mice treated with IL-10+/+ iTr...
ORGANISM(S): Mus musculus 
2012-12-06 | E-GEOD-35543 | biostudies-arrayexpress
TranscriptomicsSalmon Macrophage early response to Aeromonas salmonicida
Aeromonas salmonicida is a fish pathogen that causes furunculosis. Virulent strains of this bacterium are able to infect salmonid macrophages and survive within them, although mechanisms favouring intracellular survival are not completely understood. It is known that A. salmonicida cultured in vivo ...
ORGANISM(S): Salmo salar 
2010-05-26 | E-GEOD-8526 | biostudies-arrayexpress
TranscriptomicsFMR1 targets distinct mRNA sequence elements to regulate protein expression [PAR-CLIP]
Fragile-X Syndrome (FXS) is a multi-organ disease leading to mental retardation, macro-orchidism in males, and premature ovarian insufficiency in female carriers. FXS is also a prominent monogenic disease associated with autism spectrum disorders (ASD). FXS is typically caused by the loss of FRAGILE...
ORGANISM(S): Homo sapiens 
2012-12-13 | E-GEOD-39682 | biostudies-arrayexpress
Unknown175. Randomized Double-blind Controlled Trial of Short vs. Standard Course Outpatient Therapy of Community Acquired Pneumonia in Children (SCOUT-CAP)
Not available
S-EPMC7776421 | biostudies-literature
TranscriptomicsmodENCODE_White Lab: genome-wide ChIP-chip and ChIP-Seq data
For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2010-08-11 | E-GEOD-23537 | biostudies-arrayexpress
TranscriptomicsSystematic evaluation of variability in ChIP-chip experiments using predefined DNA targets
The most widely used method for detecting genome-wide protein-DNA interactions is chromatin immunoprecipitation on tiling microarrays, commonly known as ChIP-chip. Here, we conducted the first objective analysis of tiling array platforms, amplification procedures, and signal detection algorithms in ...
ORGANISM(S): Homo sapiens 
2010-09-30 | E-GEOD-10114 | biostudies-arrayexpress
UnknownaMPT and amphetamine ameliorate hyperactivity in a novel mouse model of DTDS
Not available
S-SCDT-10_1038-S44321-026-00381-0 | biostudies-other
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