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ProteomicsChemical crosslinking and mass spectrometry of the human Rix1 complex
PELP1 is a scaffold protein with diverse cellular functions including its role as the central scaffold for the human Rix1 complex (PELP1, WDR18, TEX10, and SENP3). We have reconstituted the mammalian Rix1 complex and identified a sub-complex made of the conserved Rix1 domain of PELP1 and the WDR18 p...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037729 | Pride
Q-exactive Lc-ms Rix1 Protein prospector Pelp1 Bs3 Crosslinking 
UnknownLAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis.
Not available
S-EPMC3279398 | biostudies-literature
ProteomicsProteomic analysis of PELP1 (RIX1) interactome.
A mass spectrometry-based proteomic analysis of the Rix1 60S biogenesis complex through immunoprecipitation of endogenous PELP1 from HEK293T cells.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-12-03 | MSV000096583 | MassIVE
GenomicsNuclear peripheral positioning of heterochromatin by Amo1NUPL2 suppresses nucleosome turnover to promote epigenetic inheritance [ChIP-seq]
Occupancy profiling of GFP-tagged Rix1 protein in fission yeast.
ORGANISM(S): Schizosaccharomyces pombe 
2020-01-11 | GSE141070 | GEO
GenomicsNuclear peripheral positioning of heterochromatin by Amo1NUPL2 suppresses nucleosome turnover to promote epigenetic inheritance [ChIP-chip_C300]
Occupancy profiling of GFP-tagged Rix1, Las1, Ipi1, Crb3 proteins in fission yeast. Occupancy profiling of lysine 9 trimethylated histone H3 in fission yeast.
ORGANISM(S): Schizosaccharomyces pombe 
2020-01-11 | GSE132862 | GEO
UnknownCryo-EM reveals the architecture of the PELP1-WDR18 molecular scaffold.
Not available
S-EPMC9646879 | biostudies-literature
ProteomicsChromatin-associated RNA degradation contributes to silencing of Polycomb target genes
Polycomb Repressive Complexes 1 and 2 (PRC1 and PRC2) are histone-modifying and -binding complexes that mediate the formation of facultative heterochromatin and are required for silencing of developmental genes and maintenance of cell fate. Multiple pathways of RNA decay work together to establish a...
ORGANISM(S): Homo sapiens (Human) 
2022-01-19 | PXD027966 | Pride
Prc2 Polycomb Prc1 Rix1 Rna degradation Rixosome 
ProteomicsThe GTPase Nog1 co-ordinates assembly, maturation and quality control of distant ribosomal functional centers
Yeast ribosome assembly analysis, using APMS on various 60S tagged subunits (SSF1, RIX1, ARX1, KRE35, ARX1_bud20D, KRE35_DRG1, KRE35_drg-dn, YEP, G223, NOG1)
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-01-06 | PXD011382 | Pride
Ribosome Apms S cerevisiae 60s 
GenomicsNuclear peripheral positioning of heterochromatin by Amo1NUPL2 suppresses nucleosome turnover to promote epigenetic inheritance [ChIP-seq]
Nuclear peripheral positioning of heterochromatin by Amo1NUPL2 suppresses nucleosome turnover to promote epigenetic inheritance [ChIP-seq]
PRJNA591922 | ENA
UnknownProline-, Glutamic Acid-, Leucine-Rich Protein 1 (PELP1): Diversity, Structural Conservation, and Evolutionary Origins Across the Species.
Not available
S-EPMC12733202 | biostudies-literature
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