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GenomicsRNA-seq profiling of mouse embyonic fibroblasts treated with the Myst inhibitor WM-8014
RNA-seq profiling of mouse embyonic fibroblasts treated with the Myst inhibitor WM-8014
PRJNA422909 | ENA
TranscriptomicsRNA-seq profiling of mouse embyonic fibroblasts treated with the Myst inhibitor WM-8014
Acetylation of histones by lysine acetyltransferases (KATs) is essential for transcriptional regulation of gene expression. The MYST family of KATs (KAT5-8) includes the oncogenes KAT6A (MOZ) and KAT6B (MORF/QKF). KAT6A has key roles in promoting cell proliferation through transcriptional activation...
ORGANISM(S): Mus musculus 
2018-08-03 | GSE108243 | GEO
ProteomicsHierarchical small molecule inhibition of MYST acetyltransferases
MYST lysine acetyltransferases (KATs) is a class of epigenetic enzymes critical for cellular function that constitute an emerging therapeutic target in cancer. Recently, several drug-like MYST inhibitors have been reported that show promise in a variety of preclinical models as well as in clinical t...
ORGANISM(S): Homo sapiens (Human) 
2026-06-01 | PXD074488 | Pride
Histone acetylation Lysine acetyltransferases Wm-1119 Wm-3835 Drug-like myst inhibitors Chemoproteomics Myst Foxk2 Pf-9363 Wm-8014 
TranscriptomicsRNA-seq profiling of a mouse B cell lymphoma cell line treated with the KAT6A/B inhibitor WM-1119
Acetylation of histones by lysine acetyltransferases (KATs) is essential for chromatin organization and function. The MYST family of KATs (KAT5-8) includes the oncogenes KAT6A (MOZ) and KAT6B (MORF/QKF). KAT6A has essential roles in normal hematopoietic stem cells and is the target of recurrent chro...
ORGANISM(S): Mus musculus 
2018-08-03 | GSE114962 | GEO
TranscriptomicsRNA-seq profiling of mouse embryonic fibroblasts treated with WM-2474 or DMSO
Acetylation of histones by lysine acetyltransferases (KATs) is essential for chromatin organization and function. The MYST family of KATs (KAT5-8) includes the oncogenes KAT6A (MOZ) and KAT6B (MORF/QKF). KAT6A has essential roles in normal hematopoietic stem cells and is the target of recurrent chro...
ORGANISM(S): Mus musculus 
2018-08-03 | GSE114963 | GEO
UnknownHierarchical small molecule inhibition of MYST acetyltransferases.
Not available
S-EPMC12478385 | biostudies-literature
ProteomicsHierarchical small molecule inhibition of MYST acetyltransferases
MYST lysine acetyltransferases (KATs) is a class of epigenetic enzymes critical for cellular function that constitute an emerging therapeutic target in cancer. Recently, several drug-like MYST inhibitors have been reported that show promise in a variety of preclinical models as well as in clinical t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-04-23 | MSV000097704 | MassIVE
GenomicsRNA-seq profiling of a mouse B cell lymphoma cell line treated with the KAT6A/B inhibitor WM-1119
RNA-seq profiling of a mouse B cell lymphoma cell line treated with the KAT6A/B inhibitor WM-1119
PRJNA473345 | ENA
GenomicsRNA-seq profiling of mouse embryonic fibroblasts treated with WM-2474 or DMSO
RNA-seq profiling of mouse embryonic fibroblasts treated with WM-2474 or DMSO
PRJNA473346 | ENA
UnknownIn Silico Study on the Interactions, Molecular Docking, Dynamics and Simulation of Potential Compounds from Withania somnifera (L.) Dunal Root against Cancer by Targeting KAT6A.
Not available
S-EPMC9920226 | biostudies-literature
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