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ProteomicsAcetylome Profiling Reveals the Endogenous Substrates of HDAC6
HDAC6 inhibitors are novel targeted therapies showing good clinical response in a variety of different malignancies. However, their use and farther development is hampered by the limited knowledge regarding what are the endogenous substrates of HDAC6 enzyme. Here we plan to complete acetylome profil...
ORGANISM(S): Homo sapiens (Human) 
2022-11-09 | PXD026010 | Pride
Mass spectrometry Hap1 cell Acetylome Proteomics 
UnknownCovalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein Inhibitors.
Not available
S-EPMC11673110 | biostudies-literature
OtherJUMP: a tag-based database search tool for peptide identification with high sensitivity and accuracy.
Data from authors [[http://stjuderesearch.org/site/lab/peng web site]]. Experiment: dataset3, file: pl08.mzXML. Published as part of Mol Cell Proteomics. 2014 Sep 8 . From the Abstract: {{i}} ... Here we present JUMP, a new hybrid database search program that generates amino acid tags and ranks pep...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320003491 | GPMDB
ProteomicsDeep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression
The molecular networks underlying Alzheimer’s disease (AD) are not well-defined. We present temporal profiling of >14,000 proteins and >34,000 phosphosites at the asymptomatic and symptomatic stages of AD, deep proteomics analysis of transgenic mouse models.
ORGANISM(S): Mus musculus (Mouse) 
2020-04-16 | PXD018590 | Pride
Tmt-lc/lc-ms/ms Brain Ad mouse model 
OtherRefined phosphopeptide enrichment by phosphate additive and the analysis of human brain phosphoproteome.
Data from ProteomeXchange, PXD ID: PXD001180. File: tio2_250ug.mzml. Published as part of Proteomics. 2015 Jan;15(2-3):500-7 . From the Abstract: {{i}} Here, we report a pilot investigation of AD phosphoproteome by titanium dioxide enrichment coupled with high resolution LC-MS/MS. During the optimi...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM11210034774 | GPMDB
Resource Reanalysis 
ProteomicsHs_Brain_Phospho
Human brain phosphoproteome analyzed by refined phosphopeptide enrichment
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005247 | PeptideAtlas
UnknownmiR-198 inhibits the progression of renal cell carcinoma by targeting BIRC5.
Not available
S-EPMC8296723 | biostudies-literature
UnknownEffectiveness and safety of blonanserin for improving social and cognitive functions in patients with first-episode schizophrenia: a study protocol for a prospective, multicentre, single-arm clinical trial.
Not available
S-EPMC9021809 | biostudies-literature
ProteomicsProteomic analysis for In situ generation of micrometer-sized tumor cell-derived vesicles as autologous cancer vaccines for boosting systemic immune responses
Proteomic analysis for In situ generation of micrometer-sized tumor cell-derived vesicles as autologous cancer vaccines for boosting systemic immune responses
ORGANISM(S): Mus Musculus 
PXD035315 |
ProteomicsJUMPg: an Integrative Proteogenomics Pipeline Identifying Unannotated Proteins in Human Brain and Cancer Cells
Proteogenomics is an emerging approach to improve gene annotation and interpretation of proteomics data. Here we present JUMPg, an integrative proteogenomics pipeline including customized database construction, tag-based database search, peptide-spectrum match filtering, and data visualization. JUMP...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-16 | MSV000080641 | MassIVE
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