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UnknownY chromosomes of 40% Chinese descend from three Neolithic super-grandfathers.
Not available
S-EPMC4149484 | biostudies-literature
ProteomicsHigh-risk EBV promotes immune evasion in nasopharyngeal carcinoma by upregulating HLA-DP via the encoded BALF2-HR variant
Nasopharyngeal carcinoma (NPC) is prevalent in East and Southeast Asia, with genetic factors playing a significant role in its occurrence. The HLA gene region on chromosome 6 is linked to NPC susceptibility, but the mechanisms remain unclear. Epstein-Barr virus (EBV) infection is a well-established ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-17 | PXD074503 | Pride
Nasopharyngeal carcinoma Immune evasion Balf2 High-risk ebv subtype Hla-dp 
UnknownPhase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy.
Not available
S-EPMC3157979 | biostudies-literature
UnknownDetection of Herbal Combinations and Pharmacological Mechanisms of Clinical Prescriptions for Coronary Heart Disease Using Data Mining and Network Pharmacology.
Not available
S-EPMC8557045 | biostudies-literature
TranscriptomicsIdentification of glucose-TOR signaling early target genes in Arabidopsis seedling autotrophic transition stage
The goal of this experiment was to explore the molecular network of glucose-TOR signaling in Arabidopsis seedling autotrophic transition stage. We used the whole-genome microarrays to detail the global program of gene expression mediated by glucose and TOR. Arabidopsis WT and estradiol inducible RNA...
ORGANISM(S): Arabidopsis thaliana 
2013-04-05 | E-GEOD-40245 | biostudies-arrayexpress
UnknownAmeliorating Effects of Vitamin K2 on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.
Not available
S-EPMC9917520 | biostudies-literature
TranscriptomicsLarge-scale multi-species survey of metabolome and lipidome
This dataset was generated with the goal of comparative study of gene expression in three brain regions and two non-neural tissues of humans, chimpanzees, macaque monkeys and mice. Using this dataset, we performed studies of gene expression and gene splicing evolution across species and search of ti...
ORGANISM(S): Macaca mulatta 
2014-05-30 | E-GEOD-49379 | biostudies-arrayexpress
ProteomicsIdentification of ADAM12S-interacting proteins in HeLa cells
ADAM12 is an A Disintegrin And Metalloproteinases (ADAMs). It is composed of signaling sequence, prodomain, metalloproteinase, disintegrin, cysteine-rich, EGF-like, transmembrane domains, and a cytoplasmic tail. ADAM12 is highly expressed in multiple cancers and is a diagnostic and prognostic biomar...
ORGANISM(S): Homo sapiens (Human) 
2022-02-28 | PXD009078 | Pride
Hela Interacting proteins Lc-ms/ms Adam12s Label free quantification 
ProteomicsIP-MS of DCAF1/VprBP interacting proteins in mouse CD4 T cells
DCAF1, also known as VprBP (HIV-1-viral-protein-r-binding-protein), is an evolutionary conserved substrate-binding subunit of CRL4 (Cul4a-Ddb1-Roc1) ubiquitin ligase complex. It is a cellular protein targeted by HIV-1 viral protein R (Vpr). DCAF1 modulates cellular response against HIV in macrophage...
ORGANISM(S): Mus musculus (Mouse) 
2016-01-12 | PXD003180 | Pride
Dcaf1 T cell Vprbp Hiv-1 
UnknownThe roles of NHEJ and TLS pathways in genomic alterations and phenotypic evolution in the yeast Yarrowia lipolytica.
Not available
S-EPMC12354579 | biostudies-literature
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