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ProteomicsEZH2 pre-mRNA pull-down screening for proteins that regulate EZH2 alternative splicing
Post-transcriptional regulation mediated by RNA-binding proteins is essential for B cell development and differentiation. EZH2 is a key regulatory protein involved in B cell development and the germinal center response, and its expression is subject to alternative splicing regulation. Skipping of ex...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-30 | PXD077818 | Pride
Pull down Ezh2 
UnknownNeoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): A Phase III Multicenter, Randomized, Open-Label Clinical Trial.
Not available
S-EPMC6145832 | biostudies-literature
ProteomicsRepurposing Lusutrombopag: Unveiling Anti-Staphylococcus aureus Activity in a Novel Oral Thrombopoietin Receptor Agonist
Here are the findings from the DARTs (Drug Affinity Responsive Target Stability) and proteomics studies for Lusutrombopag
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Nctc 8325 
2025-12-17 | PXD072172 |
ProteomicsMLS0315771 S. aureus YUSA145 proteomics
Quantitative label-free proteomic analysis investigated the global proteomic response of S. aureus YUSA145 treated with 1/2 × MIC MLS0315771 during the exponential growth phase. The results were obtained after performing principal component analysis (PCA) on the raw data and excluding two replicates...
ORGANISM(S): Staphylococcus Aureus 
2026-01-24 | PXD073535 |
ProteomicsMass spectrometry analysis of proteins interacting with Fbxw7 in T cells
To elucidate how gut microbiota (GM) downregulated Fbxw7, we treated CD4+ T cells with GM-lysates and pulled down Fbxw7 in the cell lysates. Then, the precipitated proteins were analyzed by mass spectrometry, and eight E3 ligases were revealed to interact with Fbxw7.
ORGANISM(S): Mus musculus (Mouse) 
2025-04-16 | PXD057140 | Pride
Fbxw7  trim21  th17 cells  gut microbiota 
UnknownElectrochemical N-N Oxidatively Coupled Dehydrogenation of 3,5-Diamino-1<i>H</i>-1,2,4-triazole for Value-Added Chemicals and Bipolar Hydrogen Production.
Not available
S-EPMC11926877 | biostudies-literature
ProteomicsComparison of the significantly differentially expressed protein between K2044, K2044-8Xyl-60G, K2044-ΔXylA and K2044-ΔXylB treated with 8% xylose
The K. pneumoniae K2044, K2044-8Xyl-60G, K2044-ΔXylA and K2044-ΔXylB isolates were cultured overnight in MRS medium, then 1:200 diluted in MRS medium with 8% xylose to reach the exponential growth phase. The control group was K2044 treated with 8% xylose. The experiment was performed in triplicate.
ORGANISM(S): Klebsiella Pneumoniae 1191100241 
2024-11-04 | PXD057506 |
ProteomicsProteomic response of S. aureus to alpha-mangostin
S. aureus isolate was inoculated and cultured to exponential growth phase (OD600 at 0.5) in TSB and divided into two groups, the control group and the drug treated group. alpha-mangostin was added to the drug treated group until a final concentration of 1/2× MIC reached, and DMSO added in the contro...
ORGANISM(S): Staphylococcus Aureus 
2022-10-17 | PXD037518 |
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