Sort   by:  
 Page size 
ProteomicsIWS1 Stimulates Pol II Transcription Elongation In Vivo (revision data)
The protein IWS1 (Interacts with SPT6 1) has been implicated in various transcription-associated processes, but whether it has a direct role in RNA polymerase (Pol) II transcription remains unclear. Here, we establish a rapid depletion system for IWS1 in human cells, and use it to elucidate its func...
ORGANISM(S): Homo sapiens (Human) 
2025-07-30 | PXD066658 | Pride
Proteomis Iws1 Chromatin 
ProteomicsIWS1 Stimulates Pol II Transcription Elongation In Vivo
The protein IWS1 (Interacts with SPT6 1) has been implicated in various transcription-associated processes, but whether it has a direct role in RNA polymerase (Pol) II transcription remains unclear. Here, we establish a rapid depletion system for IWS1 in human cells, and use it to elucidate its func...
ORGANISM(S): Homo sapiens (Human) 
2025-07-30 | PXD056248 | Pride
Transcriptional elongation Transcription Rna polymerase ii Histone modifications H3k36me3 Setd2 Iws1 
ProteomicsProteomic, phosphoproteomic and N-glycoproteomic analysis of small extracellular vesicles (sEVs) from C2C12 myoblasts
We conducted a comprehensive and integrated proteomic，phosphoproteomic, N-glycoproteomic analysis of the cargos in small extracellular vesicles (sEVs)-derived from C2C12 myoblasts.
ORGANISM(S): Mus Musculus 
2023-12-20 | PXD047974 |
ProteomicsComprehensive evaluation of different TiO2-based phosphopeptide enrichment and fractionation methods for phosphoproteomics
We performed a comprehensive evaluation of four different TiO2-based phosphopeptide enrichment methods using different non-phosphopeptide excluders. Then, two phosphopeptide fractionation methods, including the ammonia-based and the TEA based high pH reversed-phase fractionation, are also evaluated.
ORGANISM(S): Homo Sapiens 
2022-06-02 | PXD034264 |
ProteomicsNovel Peptidomic Analysis Identifies Peptide Clusters with Potential for Disease Diagnosis and Dysregulated Proteolytic Processing
Mass spectrometry-based peptidomics provides a comprehensive approach to delineate the global proteolytic landscape of diseases and to identify potential biomarkers. However, current data analysis methods struggle to distill the peptidomic signatures of diseases. In this study, we conducted a peptid...
ORGANISM(S): Homo Sapiens 
2025-04-02 | PXD062496 |
Proteomicsβ-thalassemia plasma EVs proteomics
Here, we performed plasma extracellular vesicles (EVs) proteomics on 20 β-thalassemia major (TM) patients, 20 intermedia (TI) patients, and 20 healthy controls to explore the subgroup characteristics and the potential biomarkers. The proteome of paired plasma was analyzed in parallel to compare the ...
ORGANISM(S): Homo Sapiens 
2022-06-15 | PXD034548 |
Sort   by:  
 Page size