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ProteomicsProteomics and phosphoproteomics reveal immune and detoxification-related functions of cystatin vaccines against adult ticks Haemaphysalis doenitzi ovary
Proteomics and phosphoproteomics reveal immune and detoxification-related functions of cystatin vaccines against adult ticks Haemaphysalis doenitzi ovary
ORGANISM(S): Haemaphysalis Doenitzi 
2024-08-28 | PXD055423 |
ProteomicsIntradermal Delivery of Catalase via Extracellular Vesicles for Targeted Photoaging Therapy
We engineered a 313-cell line to produce EVs that were subsequently loaded with catalase (CAT), a key antioxidant enzyme. These CAT-loaded EVs (313EVs) exhibited high loading efficiency and maintained both vesicle integrity and enzymatic activity
ORGANISM(S): Rattus Norvegicus 
2025-12-12 | PXD072392 |
ProteomicsProteomic analysis of human Wharton's jelly mesenchymal stem cells and human amniotic epithelial stem cells: a comparison of therapeutic potential
proteomics analysis of human umbilical cord mesenchymal stem cells and human amniotic epithelial stem cells
ORGANISM(S): Homo Sapiens 
2024-06-05 | PXD052844 |
ProteomicsProteomic analysis of human Wharton's jelly mesenchymal stem/stromal cells and human amniotic epithelial stem cells: a comparison of therapeutic potential
Background: Perinatal stem cells have prominent applications in cell therapy and regenerative medicine. Among them, human Wharton's jelly mesenchymal stem/stromal cells (hWJMSCs) and human amniotic epithelial stem cells (hAESCs) are widely used. However, little is known about the dif-ferences in the...
ORGANISM(S): Homo Sapiens 
2023-08-02 | PXD044276 |
Proteomics[HPP-2.0] Proteomics profiling of HIV-1-associated colorectal cancer
HIV-1 infected patients have significantly higher chance to get cancers such as CRC and lung cancer that are not defined in HIV-1/AIDS. However, the systems biological understanding of these HIV-1 associated malignancies (HAM) has not been clearly addressed so far. To this end, we have finished prot...
ORGANISM(S): Homo Sapiens 
2023-09-20 | PXD045515 |
ProteomicsChaperone-mediated autophagy supports organ regeneration and fibroblast quiescence in mouse models of fibrosis
Chaperone-mediated autophagy (CMA) acting as a crucial, selective protein degradation pathway is a key topic in understanding tissue remodeling and disease, with recent research showing its pivotal role in maintaining organ health, particularly through the maintenance of fibroblast quiescence and su...
ORGANISM(S): Mus Musculus 
2026-01-22 | PXD073386 |
ProteomicsKLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells
Vascular smooth muscle cells (VSMCs) within atherosclerotic lesions undergo a phenotypic switching in a KLF4-dependent manner. Glycolysis plays important roles in transdifferentiation of somatic cells, however, it is unclear whether and how KLF4 mediates the link between glycolytic switch and VSMCs ...
ORGANISM(S): Homo Sapiens 
2022-11-09 | PXD038057 |
ProteomicsAML cell line THP-1 shControl VS THP-1 shPSMB10
In the THP-1 cell line, knockdown of PSMB10 expression was performed using lentivirus, with a control group set up.
ORGANISM(S): Homo Sapiens 
2024-12-10 | PXD058714 |
ProteomicsHypoxia Regulates Overall mRNA Homeostasis by Inducing Met1-linked Linear Ubiquitination of AGO2 in Cancer Cells
Hypoxia is the most prominent feature in human solid tumors and induces activation of hypoxia-inducible factors and their downstream genes to promote cancer progression. However, whether and how hypoxia regulates overall mRNA homeostasis is unclear. Here we show that hypoxia inhibits global-mRNA dec...
ORGANISM(S): Homo Sapiens 
2021-04-06 | PXD021722 |
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