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ProteomicsBiogenesis and migration of the sperm cytoplasmic droplet requires ARRDC5 and TEX38
The maturation of spermatid to fertilization competent spermatozoa is a sophisticated process required for sexual reproduction, and biogenesis of the cytoplasmic droplet (CD) is a key event. Here we demonstrate that two proteins with testis-specific expression, ARRDC5 and TEX38, physically interact,...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-02 | PXD063909 | Pride
Cytoplasmic droplet Lc-ms Arrdc5-/- or tex38-/- mice Spermatid Spermatozoa 
ProteomicsDrosophila melanogaster LC-MSMS
we performed proteome sequencing in Drosophila at day 7 (young) and day 42 (old) under dietary restriction (DR)and ad libitum (AL) conditions.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-09-09 | PXD021022 | Pride
Lc-msms Drosophila Plasma 
ProteomicsSerum metabolomics reveal metabolic changes in coal workers’ pneumoconiosis progression
The raw data of coal workers pneumoconiosis serum metabolomics
ORGANISM(S): Homo Sapiens 
PXD068448 |
UnknownMetaDiff: differential isoform expression analysis using random-effects meta-regression.
Not available
S-EPMC4489045 | biostudies-literature
ProteomicsProteome, lysine acetylome and succinylome identify post-translational modification of STAT1 as a novel drug target in silicosis
Inhalation of crystalline silica dust induces incurable lung damage, silicosis and pulmonary fibrosis. However, the mechanisms of the lung injury remain poorly understood, with limited therapeutic options aside from lung transplantation. Post-translational modifications can regulate the function of...
ORGANISM(S): Mus Musculus 
2024-02-04 | PXD049146 |
UnknownInferring super-resolution tissue architecture by integrating spatial transcriptomics with histology.
Not available
S-EPMC11260191 | biostudies-literature
ProteomicsProteome and phosphoproteome landscape of silicosis occurrence in mice model
To map the multi-omics atlas of silicosis progression, we collected four replicates of whole lung lobes from mice at different stages (W2, W4, W6, W10) after silica-treated as well as W6 after PBS-treated (as control). Then we performed (phospho) proteome analysis as well as bioinformatic analysis.
ORGANISM(S): Mus Musculus 
2021-08-04 | PXD027693 |
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