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MetabolomicsPlasma metabolome alteration in dairy cows with left displaced abomasum before and after surgical correction
Left displaced abomasum (LDA) leads to substantial changes in the metabolism of dairy cows. Surgical correction of LDA can rapidly improve the health of cows; however, changes in metabolism following surgery are rarely described. To investigate the changes of plasma metabolome in cows with LDA befor...
2022-08-17 | MTBLS4126 | MetaboLights
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type and opaque2 mutant Transcriptomes
Analysis of gene expression level. The hypothesis tested in the present study was that opaque2 mutant influence the expression of storage proteins. Results provide important information of the gene expression level regulation of storage proteins and other biological processes. Endosperm mRNA profil...
ORGANISM(S): Zea mays 
2014-10-15 | E-GEOD-61830 | biostudies-arrayexpress
TranscriptomicsTracing pluripotency of human early embryos and embryonic stem cells by single cell RNA-seq
Find the casual relationship between gene expression network and cellular phenotype at single cell resolution. We collected donated human pre-implatation embryos, and the embryonic stem cells derived from them, isolate individual cells, prepared single cell cDNAs, and sequenced them by HiSeq2000. Th...
ORGANISM(S): Homo sapiens 
2013-08-10 | E-GEOD-36552 | biostudies-arrayexpress
ProteomicsA genetic model for in vivo proximity labeling of the mammalian secretome
Yang R, Meyer AS, Droujinine I, Udeshi ND, Hu Y, Guo J, McMahon J, Carey DK, Xu C, Qiao F, Sha J, Qin S, Rocco D, Wohlschlegel J, Ting AY, Carr SA, Perrimon N, McMahon AP. 2022. Organ functions are highly specialized and interdependent. Tissue-specific secreted factors play a critical role in organ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-02-16 | MSV000088848 | MassIVE
UnknownModulation of PD-L1 by Astragalus polysaccharide attenuates the induction of melanoma stem cell properties and overcomes immune evasion.
Not available
S-EPMC11340040 | biostudies-literature
TranscriptomicsRNA-seq analysis of gene expression patterns responding to TSA treatment during hESC neural differentiation
We report the differential roles of an HDAC inhibitor-TSA during hESC nerual commitment. In the initiation of hESC differentiation, TSA could inhibit the downregulation of pluripotency genes to maintain pluripotency, whereas in the neural commitment stage, TSA could promote neural gene expression to...
ORGANISM(S): Homo sapiens 
2015-03-11 | E-GEOD-66777 | biostudies-arrayexpress
ProteomicsHuman normal and peritumor liver tissues LC-MSMS
The tumor microenvironment (TME) plays an important role in tumorigenesis1. The TME is usually studied in tumor tissue and in relation to tumor progression2,3, which can limit understanding of how the TME is involved in processes associated with initial tumorigenesis as well as tumor recurrence and ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD023118 | Pride
Human Lc-msms Hcc Liver 
ProteomicsUSP13 dictates RAN turnover and vulnerability to ferroptosis in diffused large B cell lymphoma (DLBCL)
To identify the substrates of deubiquitinase USP13, we used a protein label-free quantitation technique, which involves mass spectrometry analysis of peptides from protein digests using liquid chromatography, to identify candidate substrates of USP13 that interact with it from co-immunoprecipitation...
ORGANISM(S): Homo sapiens (Human) 
2025-12-08 | PXD056804 | Pride
Usp13 Dlbcl Ip-ms 
ProteomicsUSP13 dictates RAN turnover and vulnerability to ferroptosis in diffused large B cell lymphoma (DLBCL)
To identify the substrates of deubiquitinase USP13, we used a protein label-free quantitation technique, which involves mass spectrometry analysis of peptides from protein digests using liquid chromatography, to identify candidate substrates of USP13 that interact with it from co-immunoprecipitation...
ORGANISM(S): Homo sapiens (Human) 
2025-12-08 | PXD056840 | Pride
Usp13 Dlbcl Ip-ms 
Proteomicsplasma-derived exosomes from healthy and osteosarcoma
Identification of proteins from plasma-derived exosomes of from healthy controls and osteosarcoma patients by LC-MS/MS in label-free quantification.
ORGANISM(S): Homo sapiens (Human) 
2021-07-02 | PXD024072 | Pride
Lc-ms/ms Exosomes Proteomics analysis 
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