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Germinal center (GC) response requires increased protein synthesis. We identify the methyltransferase METTL1 as a translational checkpoint during GC responses. Therefore, we immunized mettl1-cko mice and control mice with NP-OVA, and sorted spleen B cells on day 14.
ORGANISM(S): Mus musculus (Mouse) 
2024-11-01 | PXD057426 | Pride
The mass spectrometry proteomics data of outer membrane vesicles of wide-type Escherichia coli Nissle 1917 and engineered Escherichia coli Nissle 1917
ORGANISM(S): Escherichia Coli 
2024-05-30 | PXD053377 |
Dynamic control of gene expression is crucial for most aspects of cell physiology and at its core is RNA polymerase II (RNAPII). Using 53 RNAPII point mutants, we generated a point mutant epistatic miniarray profile (pE-MAP) comprising ~60,000 quantitative genetic interactions in Saccharomyces cere...
ORGANISM(S): Saccharomyces cerevisiae 
For metabolic profiling of human CD4+ T cells,stable isotope labeling (SIL) and metabolomics SIL experiments were performed with in vitro-activated T cells using liquid chromatography (LC) coupled to mass spectrometry (MS).
ORGANISM(S): Homo Sapiens 
2024-08-24 | PXD055329 |
For metabolic profiling of mouse CD4+ T cells, stable isotope labeling (SIL) experiments were performed with in vitro-activated T cells using gas chromatography (GC) coupled to mass spectrometry (MS).
ORGANISM(S): Mus Musculus 
2024-08-24 | PXD055328 |
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