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ProteomicsProteome-wide profiling of Readers for DNA modification
Abstract DNA modifications, represented by methylcytosine (5mC), and its oxidized derivatives, such as hydroxymethylcytosine (5hmC), formylcytosine (5fC), and carboxylcytosine (5caC), play important roles in epigenetic regulation of biological processes. The specific recognition of DNA modifications...
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-05-30 | PXD026362 |
ProteomicsRegion and cell-type resolved multi-omic altas of the heart
This work presented the panoramic heart proteome map, and served as the rich resource for heart researches in the future.
ORGANISM(S): Homo Sapiens Rattus Norvegicus Mus Musculus 
2025-02-17 | PXD060863 |
ProteomicsQuartet Protein Reference Materials for Multi-platform Assessment of Label-free Proteomics
We developed the Quartet as a bulk of proteome reference materials with built-in truth, and distributed the same aliquots to 15 laboratories in six cities of China with nine conventional LC-MS/MS platforms. Relative protein abundances from over 12,000 proteins on 816 MS files were obtained and compa...
ORGANISM(S): Homo Sapiens 
PXD043262 |
ProteomicsA proteomic landscape of macrophage in mouse tissues
Macrophages, locating in essentially all tissues, are critical for innate immune responses and involved in the tissue homeostasis. Distinct macrophages populations in different tissues exhibited diverse gene expressions and biological processes. Previous studies have accessed the molecular signature...
ORGANISM(S): Mus Musculus 
PXD021583 |
ProteomicsProteogenomics of diffuse gliomas reveal molecular subtypes associated with specific therapeutic targets and immune-evasion mechanisms
This dataset include the proteomic data of 243 glioma tumor tissues (discovery: 187, validation: 56); 56 tumor-adjacent tissues (discvoery: 35, validation: 21); 12 normal brain tissues; corresponding phosphoproteomic data
ORGANISM(S): Homo Sapiens 
2022-12-12 | PXD038732 |
ProteomicsProteomics of the Gastric cancer Response to Chemotherapy
Herein, we set out to investigate the responses to first-line therapies (DOS, XELOX, and anti-HER2-based therapies) for GC through a comprehensive proteomic analysis. We constructed a GC cohort that covered three clinical therapy subcohorts, including a DOS subcohort (44 patients treated with DOS th...
ORGANISM(S): Homo Sapiens 
PXD024255 |
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