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ProteomicsProteomic Analysis Muscle and Fat Deposition in Muscovy duck
The liver responsible for 90% lipid synthesis in poultry thus plays important role in the growth of Muscovy duck, which obtains high-fat deposition ability in a time-dependent manner. Therefore, male Muscovy ducks at the age of 14, 28, 42, and 56 days were selected for body weight (BW), carcass weig...
ORGANISM(S): Anas Platyrhynchos 
PXD025920 |
ProteomicsProteomics of normal and atretic follicles in geese
Follicular atresia is an important factor affecting reproductive performance. In birds, less than 5% of follicles could complete their development process and mature ovulation, while the other 95% become atretic follicles and eventually degraded3. Yangzhou geese are famous for their high egg product...
ORGANISM(S): Anser Canagica 
PXD028836 |
ProteomicsProteome-wide profiling of Readers for DNA modification
Abstract DNA modifications, represented by methylcytosine (5mC), and its oxidized derivatives, such as hydroxymethylcytosine (5hmC), formylcytosine (5fC), and carboxylcytosine (5caC), play important roles in epigenetic regulation of biological processes. The specific recognition of DNA modifications...
ORGANISM(S): Homo Sapiens Mus Musculus 
PXD026362 |
ProteomicsProteogenomic landscape of the Esophageal Squamous Cell Cancer reveals the lipid droplet formation process as a novel therapeutic target
The integrated proteogenomic analysis revealed proteomic characteristics associated with genomic variants and clinical features including arm or focal amplifications, SNV mutations, tumor size, lymph node metastasis, smoking history.
ORGANISM(S): Homo Sapiens 
2025-03-24 | PXD062163 |
ProteomicsQuartet Protein Reference Materials for Multi-platform Assessment of Label-free Proteomics
We developed the Quartet as a bulk of proteome reference materials with built-in truth, and distributed the same aliquots to 15 laboratories in six cities of China with nine conventional LC-MS/MS platforms. Relative protein abundances from over 12,000 proteins on 816 MS files were obtained and compa...
ORGANISM(S): Homo Sapiens 
PXD043262 |
ProteomicsComprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes
A comprehensive proteomic and genomic analysis of 438 trace tumor samples from 156 duodenal cancers, covering all 8 major histopathology stages of 2 major and 5 rare subtypes in 23 substages via pathological dissection.
ORGANISM(S): Homo Sapiens 
2022-12-16 | PXD038867 |
ProteomicsProteomic analysis reveals key differences between squamous cell carcinomas and adenocarcinomas across multiple tissues
To explore the biological insights into squamous cell carcinoma (SCC) derived from different organs, we reported a deep proteomic analysis of 333 SCCs of 17 organs and 69 adenocarcinomas (ACs) of 7 organs. Proteomic comparison between pan-SCCs and pan-ACs identifies distinguishable pivotal pathways,...
ORGANISM(S): Homo Sapiens 
2022-05-19 | PXD033794 |
ProteomicsA proteomic landscape of macrophage in mouse tissues
Macrophages, locating in essentially all tissues, are critical for innate immune responses and involved in the tissue homeostasis. Distinct macrophages populations in different tissues exhibited diverse gene expressions and biological processes. Previous studies have accessed the molecular signature...
ORGANISM(S): Mus Musculus 
PXD021583 |
ProteomicsIntegrative Proteogenomic Characterization of Early Esophageal Cancer
A comprehensive proteogenomic analysis of 786 trace-tumor-samples from 154 esophageal cancers, covering all 9 major histopathology stages and 22 substages via pathological dissection.
ORGANISM(S): Homo Sapiens 
2022-12-20 | PXD038961 |
ProteomicsProteomics of the Gastric cancer Response to Chemotherapy
Herein, we set out to investigate the responses to first-line therapies (DOS, XELOX, and anti-HER2-based therapies) for GC through a comprehensive proteomic analysis. We constructed a GC cohort that covered three clinical therapy subcohorts, including a DOS subcohort (44 patients treated with DOS th...
ORGANISM(S): Homo Sapiens 
PXD024255 |
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