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ProteomicsAnalysis of circ101093 binding proteins in A549 cells after RNA pull-down.
We used circular RNA 101093 and its antisense to perform RNA pull-down, and analyzed the peptides in blank group, antisense group and circular RNA 101093 group. The object of this group is to analyze circ101093-binding protein. Blank and antisense group are used as negative control group.
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD025575 | Pride
Cancer Circular rna Fabp3 Luad Rna pull-down 
ProteomicsCirc101093 regulated proteins in Lung carcinoma (LUAD) cells.
Circ101093 was knocked down in A549 LUAD cell lines, and overexpressed in H1975 LUAD cell lines. Then, downregulated proteins in A549 cell lines and upregulated proteins in H1975 cell lines were analyzed.
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD025491 | Pride
A549 h1975 Cell line. Keywords: circular rna Luad Fabp3 
ProteomicsMass spectrometry for the proteomics following RNA pull down of m6A methylated RN7SK in lung adenocarcinoma A549 cell line.
The aim of this project was to investigate the proteins that bind to m6A methylated RN7SK in lung adenocarcinoma A549 cell line. And mass spectrometry of A549 cell treated with or without m6A methylated RN7SK in three replicates.
ORGANISM(S): Homo Sapiens 
2022-04-12 | PXD033184 |
Proteomicsproteomics of m6A-High and m6A-Low LUAD tissues
The dataset includes the sequencing data of m6A-high and m6A-low LUAD tissues, each of which contains five biological replicates. A total of 3437 protein groups were obtained, 407 differential proteins were obtained . Exerllent repeatability for different biological replicates is indicated based on...
ORGANISM(S): Homo Sapiens 
2021-07-29 | PXD027633 |
ProteomicsProteomic analysis of human Wharton's jelly mesenchymal stem cells and human amniotic epithelial stem cells: a comparison of therapeutic potential
proteomics analysis of human umbilical cord mesenchymal stem cells and human amniotic epithelial stem cells
ORGANISM(S): Homo Sapiens 
2024-06-05 | PXD052844 |
ProteomicsProteomic analysis of human Wharton's jelly mesenchymal stem/stromal cells and human amniotic epithelial stem cells: a comparison of therapeutic potential
Background: Perinatal stem cells have prominent applications in cell therapy and regenerative medicine. Among them, human Wharton's jelly mesenchymal stem/stromal cells (hWJMSCs) and human amniotic epithelial stem cells (hAESCs) are widely used. However, little is known about the dif-ferences in the...
ORGANISM(S): Homo Sapiens 
2023-08-02 | PXD044276 |
ProteomicsLoss of Fbxo45 in AT2 cells leads to insufficient histone supply and initiates lung adenocarcinoma
We identified proteins that interact with FBXO45 and UPF1 through mass spectrometry.
ORGANISM(S): Homo Sapiens 
2024-10-29 | PXD057326 |
ProteomicsHypoxia Regulates Overall mRNA Homeostasis by Inducing Met1-linked Linear Ubiquitination of AGO2 in Cancer Cells
Hypoxia is the most prominent feature in human solid tumors and induces activation of hypoxia-inducible factors and their downstream genes to promote cancer progression. However, whether and how hypoxia regulates overall mRNA homeostasis is unclear. Here we show that hypoxia inhibits global-mRNA dec...
ORGANISM(S): Homo Sapiens 
2021-04-06 | PXD021722 |
ProteomicsKLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells
Vascular smooth muscle cells (VSMCs) within atherosclerotic lesions undergo a phenotypic switching in a KLF4-dependent manner. Glycolysis plays important roles in transdifferentiation of somatic cells, however, it is unclear whether and how KLF4 mediates the link between glycolytic switch and VSMCs ...
ORGANISM(S): Homo Sapiens 
2022-11-09 | PXD038057 |
ProteomicsHippocampal proteomics analysis of marginal zinc deficiency
Zinc is an essential trace element that is closely related to learning and memory ability. The hippocampus plays an important role in learning and memory and has the highest zinc concentration in the brain. Severe zinc deficiency (zinc-deprived diet) significantly alter hippocampal protein expressio...
ORGANISM(S): Rattus Norvegicus 
2021-10-04 | PXD028998 |
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