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MetabolomicsMechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis

Zhuyu pill (ZYP) is a traditional Chinese medicine prescription composed of two drugs, Coptis chinensis Franch. and Tetradium ruticarpum (A. Jussieu) T. G. Hartley, and is commonly used in the clinical treatment of diseases of the digestive system. However, the mechanism underly...

2022-11-02 | MTBLS4980 | MetaboLights
ProteomicsCandidate proteins involved in the calyx abscission process of ‘Kuerlexiangli’ (Pyrus sinkiangensis Yu) identified by iTRAQ analysis
‘Kuerlexiangli’ (Pyrus sinkiangensis Yu) is an important market pear in China. The shape and quality of the fruit is negatively affected by the presence of a persistent calyx. Here, to explore the molecular mechanism of calyx abscission, we designed an experiment to compare protein expression at two...
ORGANISM(S): Pyrus x bretschneideri 
2020-06-17 | PXD012499 | Pride
Itraq Pear Calyx abscission Differentially abundant proteins 
TranscriptomicsCXCR5+ Follicular Cytotoxic T cells Control Viral Infection in B Cell follicles
Lymphocytic Choriomeningitis Virus (LCMV) specific CD8+ T cells (P14) were transferred into congenic WT mice followed by LCMV(DOCILE) infection. CXCR5-expressing (CXCR5+) or CXCR5 non-expressing (CXCR5-) P14 were purified on day 8 after infection, and total mRNA were sequenced from these populations...
ORGANISM(S): Mus musculus 
2016-07-31 | E-GEOD-76279 | biostudies-arrayexpress
UnknownDownregulation of KIF1B mRNA in hepatocellular carcinoma tissues correlates with poor prognosis.
Not available
S-EPMC4507112 | biostudies-literature
UnknownJoint Association of Dietary Protein Intake and Eating Habits with the Risk of Gestational Diabetes Mellitus: A Case-Control Study.
Not available
S-EPMC10610363 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis steroid inducible RGA expressor transgenic to identify RGA downstream genes
To understand the transcriptional program controlled by RGA, we took advantage of a functional steroid-inducible RGA proteins system in combination with microarray analysis to identify RGA target genes. Experiment Overall Design: We firstly compared the transcriptomes in ga1-3rgargl2RGA-GR infloresc...
ORGANISM(S): Arabidopsis thaliana 
2008-06-18 | E-GEOD-10019 | biostudies-arrayexpress
ProteomicsUSP20 promotes T-ALL evolution by deubiquitinating modified HIF1A
Qualitative analysis of proteome is to study the types and quantities of proteome identified by samples under different conditions, and to perform functional analysis of the identified proteins, so as to provide reference information for quantitative and modification analysis of high-throughput prot...
ORGANISM(S): Homo sapiens (Human) 
2025-10-13 | PXD053080 | Pride
Usp20 Hif1a 
UnknownIdentification of optimal feature genes in patients with thyroid associated ophthalmopathy and their relationship with immune infiltration: a bioinformatics analysis.
Not available
S-EPMC10611488 | biostudies-literature
UnknownChemometrics integrated with in silico pharmacology to reveal antioxidative and anti-inflammatory markers of dandelion for its quality control.
Not available
S-EPMC9636813 | biostudies-literature
UnknownPLZF-expressing CD4<sup>+</sup> T cells promote tissue-resident memory T cells in breaking immune tolerance in allergic asthma via IL-15/IL-15Rα signaling.
Not available
S-EPMC11910871 | biostudies-literature
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