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ProteomicsTargeting Pim2 Improves Effector Function and Longevity of CD8 T cells in Cancer Immunotherapy
The Pim kinase family is critically involved in tumorigenesis, yet its function in primary T cells remains poorly understood. We previously reported that Pim2 negatively regulates T-cell responses to alloantigen. To investigate how Pim2 impacts anti-tumor immunity of CD8 T cells, we generated Pim2-/...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-08 | PXD059837 | Pride
Pim2 T cells Cancer Immunotherapy 
UnknownYu-Ping-Feng Formula Exerts Antilung Cancer Effects by Remodeling the Tumor Microenvironment through Regulating Myeloid-Derived Suppressor Cells.
Not available
S-EPMC8079197 | biostudies-literature
ProteomicsIntegrative Network Analysis Reveals USP7 Haploinsufficiency Inhibits E-protein Activity in Pediatric T-lineage Acute Lymphoblastic Leukemia (T-ALL)
USP7, which encodes a deubiquitylating enzyme, is among the most frequently mutated genes in pediatric T-ALL, with somatic heterozygous loss-of-function mutations (haploinsufficiency) predominantly affecting the subgroup that has aberrant TAL1 oncogene activation. Network analysis of >200 T-ALL tran...
ORGANISM(S): Homo sapiens (Human) 
2021-03-16 | PXD023377 | Pride
Tal1 T-all Usp7 
ProteomicsCandidate proteins involved in the calyx abscission process of ‘Kuerlexiangli’ (Pyrus sinkiangensis Yu) identified by iTRAQ analysis
‘Kuerlexiangli’ (Pyrus sinkiangensis Yu) is an important market pear in China. The shape and quality of the fruit is negatively affected by the presence of a persistent calyx. Here, to explore the molecular mechanism of calyx abscission, we designed an experiment to compare protein expression at two...
ORGANISM(S): Pyrus x bretschneideri 
2020-06-17 | PXD012499 | Pride
Itraq Pear Calyx abscission Differentially abundant proteins 
UnknownHigh discrimination infrared polarimetry via intrinsic anisotropic photogating in black phosphorus meta-polarization detectors.
Not available
S-EPMC12630841 | biostudies-literature
UnknownIntegrated clinical and single-cell profiling of BCMA CAR-T therapy in relapsed/refractory multiple myeloma.
Not available
S-EPMC12604393 | biostudies-literature
UnknownCircular Polarimetric Imaging with a Metamaterial Integrated Long-Wavelength Infrared Focal Plane Array.
Not available
S-EPMC12533386 | biostudies-literature
UnknownBispecific CAR-T cells targeting CD19/20 in patients with relapsed or refractory B cell non-Hodgkin lymphoma: a phase I/II trial.
Not available
S-EPMC11306243 | biostudies-literature
MetabolomicsUnraveling biomolecular and ecological mechanisms underlying the response of anammox consortia under xenobiotic stress by multi-omics strategy
Anaerobic ammonium oxidation (anammox) emerges as a sustainable solution for nitrogen removal in sewage, but it is susceptible to stress induced by xenobiotics that are ubiquitous in sewage. Despite wide recognition of this critical issue, a comprehensive understanding of the molecular and ecologica...
2026-03-27 | MTBLS14153 | MetaboLights
UnknownCritical band-to-band-tunnelling based optoelectronic memory.
Not available
S-EPMC11802729 | biostudies-literature
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