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UnknownMulti-Omics Analysis Reveals Novel Subtypes and Driver Genes in Glioblastoma.
Not available
S-EPMC7726196 | biostudies-literature
ProteomicsThe cross-linking mass spectrometry (CX-MS) results of Human TIP60 complex (hTIP60)
Mammalian TIP60 is a multi-functional enzyme with histone acetylation and histone dimer exchange activities. It plays roles in diverse cellular processes including transcription, DNA repair, cell cycle control, and embryonic development. We performed structural study on human TIP60 complex with cryo...
ORGANISM(S): Homo sapiens (Human) 
2024-07-11 | PXD048625 | Pride
Human Tip60 Cx-ms 
ProteomicsStructure of nucleosome-bound human PBAF complex
BAF and PBAF are mammalian SWI/SNF family chromatin remodeling complexes that possess multiple histone/DNA-binding subunits and create nucleosome-depleted/free regions for transcription activation. Despite previous structural studies and recent advance of SWI/SNF family complexes, it remains incompl...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036708 | Pride
Mass spectrometry analysis of acetylated nucleosome Pbaf Ncp Lc-ms 
ProteomicsRNA MS2-tag based affinity method was used to purify 3' processing factors associated with intronic PAS processing
three copies of the MS2 hairpin were fused to the intronic PAS of the nr3c1 gene. To make a negative control RNA substrate, the core hexamer AAUAAA within PAS was mutated to AACAAA. Subsequently, the RNA substrate was incubated with HeLa NE, and the mRNA 3' processing complex was purified using an M...
ORGANISM(S): Homo Sapiens 
2023-02-27 | PXD040405 |
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