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MetabolomicsMetabonomic analysis of human and 12 kinds of livestock mature milk

Mature milk, as a nutrient-rich endogenous metabolite, has various beneficial effects on the human body. In order to investigate the specific nutrients provided by different dairy products to humans, we used UHPLC-Q-TOF MS to analyze the highly significantly differentially expressed metabolites i...

2023-08-21 | MTBLS6777 | MetaboLights
MetabolomicsComparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains

Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights
UnknownTranscriptional map of 170-kb region at chromosome 11p15.5: identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples.
Not available
S-EPMC19930 | biostudies-literature
UnknownAllelic phenotype prediction of phenylketonuria based on the machine learning method.
Not available
S-EPMC10064562 | biostudies-literature
ProteomicsDeubiquitinase JOSD2 promotes non-small cell lung cancer proliferation via deubiquitylation and inactivation of LKB1
Deubiquitinases (DUBs), frequently overactivated in cancers, are associated with tumorigenesis and regarded as promising therapeutic targets. However, the underlying mechanism of DUBs promoting non-small cell lung cancer (NSCLC) are poorly understood. Through a global analysis of the contribution of...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD046139 | Pride
Deubiquitinases K6-linked polyubiquitination Non-small cell lung cancer Lkb1 Kinase activity Josd2 
UnknownαPD-1-mesoCAR-T cells partially inhibit the growth of advanced/refractory ovarian cancer in a patient along with daily apatinib.
Not available
S-EPMC7887368 | biostudies-literature
UnknownIdentification of glioblastoma gene prognosis modules based on weighted gene co-expression network analysis.
Not available
S-EPMC6211550 | biostudies-literature
ProteomicsmTORC2-driven chromatin cGAS mediates chemoresistance in colorectal cancer
Cyclic GMP-AMP synthase (cGAS), a cytosolic DNA sensor that initiates a STING-dependent innate immune response, binds tightly to chromatin, where its catalytic activity is inhibited. However, the mechanisms underlying cGAS recruitment to chromatin and the functions of chromatin-bound cGAS (ccGAS) re...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD053068 | Pride
Mtorc2 Chromatin cgas Phosphorylation Kga Chemoresistance 
UnknownCognitive behavioral therapy for adults with attention-deficit hyperactivity disorder: study protocol for a randomized controlled trial.
Not available
S-EPMC4399752 | biostudies-literature
UnknownDeciphering the transcriptomic landscape of systemic lupus erythematosus-associated pulmonary arterial hypertension.
Not available
S-EPMC11921494 | biostudies-literature
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