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MetabolomicsXMulti-omics reveals zearalenone-induced hepato-intestinal injury and growth dysregulation in largemouth bass (Micropterus salmoides)
Zearalenone (ZEN), a prevalent Fusarium-derived mycotoxin in plant protein-based aquafeeds, poses severe threats to farmed aquatic animals. However, its toxic effects and underlying mechanisms on the commercially critical largemouth bass (Micropterus salmoides) remain largely uncharacterized. Here, ...
2026-05-05 | MTBLS14430 | MetaboLights
MetabolomicsGlycosylation-mediated detoxification of zearalenone by the Tibetan yeast Hannaella zeae: Multi-omics insights into its dual-function mechanism

This study investigated the detoxification of zearalenone (ZEN) by the Tibetan Plateau yeast Hannaella zeae via untargeted LC-MS/MS-based metabolomics. H. zeae was cultured in NYDB medium with ZEN supplementation, and samples were harvested after 36 h of incubation for metabolomic analysis. The c...

2026-08-20 | MTBLS15233 | MetaboLights
MetabolomicsExplaining combinatorial effects of mycotoxins Deoxynivalenol and Zearalenone in mice with urinary metabolomic profiling
Urine metabolic profiling of mice was conducted utilizing gas chromatography-mass spectrometry (GC-MS) to investigate the combinatory effect of mycotoxins deoxynivalenol (DON) and zearalenone (ZEN) on the metabolism of the mice. Experiments were conducted by means of five-week-old mice which were in...
2021-02-11 | MTBLS580 | MetaboLights
GenomicsMouse placental microRNA profiling upon zearalenone exposure
Mouse placental microRNA profiling upon zearalenone exposure
PRJNA564853 | ENA
GenomicsCharacterization of Zearalenone-Induced Hepatotoxicity and its Mechanisms by Transcriptomics in Zebrafish Model
Characterization of Zearalenone-Induced Hepatotoxicity and its Mechanisms by Transcriptomics in Zebrafish Model
PRJNA879331 | ENA
TranscriptomicsZEA
This is a cell culture based study to asses the impact of ZEA (Zearalenone) and E. coli co-contamination on IPEC cells, these is a normal epithelial cell line isolated from a new born piglet. ZEA is a mycotoxin with a negative impact in human health. The microarray is a custom Agilent Technology arr...
ORGANISM(S): Sus scrofa 
2016-11-15 | E-MTAB-3885 | biostudies-arrayexpress
TranscriptomicsCharacterization of Zearalenone-Induced Hepatotoxicity and its Mechanisms by Transcriptomics in Zebrafish Model
Zearalenone is a mycotoxin produced by several species of Fusarium fungi, which contaminates crop and cereal products worldwide. It mainly has estrogenic, immunotoxic and xenogenic effects on various organisms. Though its hepatotoxicity has been reported by few studies, the underlying mechanisms are...
ORGANISM(S): Danio rerio 
2025-09-12 | GSE213146 | GEO
GenomicsEffect of estradiol, zearalenone and apigenin on ER-positive breast cancer cells MCF-7
Effect of estradiol, zearalenone and apigenin on ER-positive breast cancer cells MCF-7
PRJNA489503 | ENA
ProteomicsProteomic changes in HepaRG cells exposed to mycotoxins
Proteomic changes associated with the individual and combined exposures of deoxynivalenol (DON) and zearalenone (ZEA) were investigated in human hepatocytes (HepaRG cell line) after only 1h exposure and at low cytotoxicity levels using liquid chromatography coupled to tandem mass spectrometry (LC-MS...
ORGANISM(S): Homo sapiens (Human) 
2017-12-13 | PXD005840 | Pride
Co-exposure Hepatocytes Human Deoxynivalenol Zearalenone Lc-ms/ms 
UnknownRole of zearalenone lactonase in protection of Gliocladium roseum from fungitoxic effects of the mycotoxin zearalenone.
Not available
S-EPMC1796959 | biostudies-literature
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