Sort   by:  
 Page size 
ProteomicsIntegrated proteomic and transcriptomic analyses reveal the roles of Brucella BI-1 in cell division and membrane homeostasis of Brucella suis S2
To explore the role of Brucella BI-1 in Brucella suis S2, we constructed the Brucella BI-1 deletion mutant strain and its complementary strain. We then determined the effect of Brucella BI-1 deletion on the physiological characteristics of Brucella suis S2 and revealed them via integrated transcript...
ORGANISM(S): Brucella Suis Bv. 1 Str. S2 
2020-11-13 | PXD022537 |
ProteomicsUbiquitylation-omics analysis on WWP2 overexpressed mouse tubular epithelial cells (MPTCs)
WWP2 is a E3 ubiquitin ligase which may be implicated in multiple cellular event. WWP2 expressed in the kidneys and its pathological role remain to be elucidated. We performed this ubiquitylation omics analysis on renal tubular epithelial cells which overexpressd WWP2 to study WWP2's potential ubiqu...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-09 | PXD048540 | Pride
Renal tubular epithelial cells Ubiquitylation-omics 
ProteomicsQuantitative proteinomics on WWP2 overexpressed human tubular epithelial cells HK-2
WWP2 is a E3 ligase which regulates multiple cellular events, such as stress response, differentiation. WWP2 played physiological role in the distal tubules of the kidneys. Whether WWP2 regulated pathophysiological rol in the proximal tubules is unclear. In the present study, we stably overexpressed...
ORGANISM(S): Homo sapiens (Human) 
2025-06-09 | PXD048622 | Pride
Human tubular epithelial cells Wwp2 Proteinomics 
UnknownA Comparative Analysis of the Anti-Tumor Activity of Sixteen Polysaccharide Fractions from Three Large Brown Seaweed, Sargassum horneri, Scytosiphon lomentaria, and Undaria pinnatifida.
Not available
S-EPMC11278018 | biostudies-literature
MetabolomicsAnti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)

Acute kidney injury (AKI) is a known risk factor for the development of chronic kidney disease (CKD), with no satisfactory strategy to prevent the progression of AKI to CKD. Damage to the renal vascular system and subsequent hypoxia are common contributors to both AKI and CKD. Hypoxia inducible f...

2021-07-22 | MTBLS3003 | MetaboLights
MetabolomicsAnti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 10)

Acute kidney injury (AKI) is a known risk factor for the development of chronic kidney disease (CKD), with no satisfactory strategy to prevent the progression of AKI to CKD. Damage to the renal vascular system and subsequent hypoxia are common contributors to both AKI and CKD. Hypoxia inducible f...

2021-07-22 | MTBLS3056 | MetaboLights
MetabolomicsHyocholic acid species as novel biomarkers for metabolic disorders
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
TranscriptomicsAn Easy Operating Pathogen Microarray (EOPM) Platform for Rapid Screening of Vertebrate Pathogens
An Easy Operating Pathogen Microarray (EOPM) was designed to detect almost all known pathogens and related species based on their genomic sequences. For effective identification of pathogens from EOPM data, a statistical enrichment algorithm has been proposed and further implemented in a user-friend...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-45860 | biostudies-arrayexpress
TranscriptomicsDNA hypermethylation in placental tissues: placental tissues vs. maternal peripheral bloods
Noninvasive prenatal diagnosis currently used does not achieve desirable levels of sensitivity and specificity. Recently, fetal methylated DNA biomarkers in maternal whole blood have been explored for noninvasive prenatal detection. However, such efforts cover only chromosomal aneuploidy; fetal meth...
ORGANISM(S): Homo sapiens 
2012-02-22 | E-GEOD-35997 | biostudies-arrayexpress
TranscriptomicsRMECs: hypoxia-induced group vs. paired untreated group
Objective To explore the molecular mechanisms of retinopathy of prematurity (ROP) at whole genome scale using cultivated human fetal retinal microvascular endothelial cells (RMECs) under hypoxic condition. Study design Aborted fetuses with mean gestational age of 20-28 weeks at Guangdong Women and ...
ORGANISM(S): Homo sapiens 
2014-07-17 | E-GEOD-59462 | biostudies-arrayexpress
Sort   by:  
 Page size