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ProteomicsFunctional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling
Accurate chromosome segregation is coordinated by the spindle assembly checkpoint (SAC) through its effector the mitotic checkpoint complex (MCC), to inhibit the anaphase-promoting complex or cyclosome (APC/C). Cdc20 is an essential mitotic regulator since it promotes mitotic exit through activating...
ORGANISM(S): Homo sapiens (Human) 
2023-12-06 | PXD045411 | Pride
Cdc20 cry box crispr cas9 mitosis 
MetabolomicsMetabolomics reveals changes in soil metabolic profiles during vegetation succession in karst area
The metabolite characteristics of karst soils with different vegetation stages (grassland, brushwood, secondary forest and primary forest) based on untargeted metabolomics were investigated.
2025-07-07 | MTBLS10439 | MetaboLights
UnknownCanonical Correlation Analysis of Imaging Genetics Data Based on Statistical Independence and Structural Sparsity.
Not available
S-EPMC9675402 | biostudies-literature
UnknownHeat-shock chaperone HSPB1 mitigates poly-glycine-induced neurodegeneration via restoration of autophagic flux.
Not available
S-EPMC12087658 | biostudies-literature
UnknownSoluble CSF1R promotes microglial activation and amyloid clearance in alzheimer's disease.
Not available
S-EPMC12560479 | biostudies-literature
ProteomicsThe MbovP280 of mycoplasma bovis immunoprecipitates with the wole cell lysates of bovine macrophage (BoMac),and then LC-MS/MS was used to identify the MbovP280-binding ligands
An IP–MS method was used to screen for MbovP280-binding proteins. Briefly, BoMac cells were cultured, harvested, and lysed in RIPA buffer supplemented with cOmplete Protease Inhibitor Cocktail (Roche, Mannheim, Germany). The whole-cell lysates (400 μg) were incubated with 10 μg of either rMbovP280 o...
ORGANISM(S): Bos taurus (Bovine) 
2021-09-09 | PXD022080 | Pride
Lc-ms/ms Bomac Bovine Ip Mycoplasma bovis Mbovp280 
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
MetabolomicsAnalysis of fecal microbiome and metabolome changes in goats with pregnant toxemia

Pregnancy toxemia is a common disease, which occurs in older ewes that are pregnant with multiple lambs in the third trimester. Most of the sick goats die within a few days, which can seriously impact the economic benefits of goat breeding enterprises. The disease is believed to be caused by maln...

2024-10-01 | MTBLS7519 | MetaboLights
UnknownCloning and Functional Analysis of Glyoxalase I Gene <i>BrGLYI 13</i> in <i>Brassica rapa</i> L.
Not available
S-EPMC11942965 | biostudies-literature
UnknownBRD4 inhibition impairs DNA mismatch repair, induces mismatch repair mutation signatures and creates therapeutic vulnerability to immune checkpoint blockade in MMR-proficient tumors.
Not available
S-EPMC10124306 | biostudies-literature
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