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TranscriptomicsEffect of probiotic Lactobacillus casei Zhang on liver gene expression of hypercholesterolemic rats
The hypocholesterolemic effect of probiotics has been observed, but the molecular mechanism of probiotic-host interaction is still obscure. In this study, DNA microarray technology was used to explore the gene expression profile of liver of hypercholesterolemic rats caused by administration of probi...
ORGANISM(S): Rattus norvegicus 
2011-12-31 | E-GEOD-23740 | biostudies-arrayexpress
ProteomicsProteomic analysis of storage properties of Lacticaseibacillus paracasei Zhang starter culture by DNA methylation
This study took the advantage of the availability of a methylated mutant (ΔpglX ) of Lacticaseibacillus (L.) paracasei Zhang to test our hypothesis that DNA methylation could protect lactic acid bacteria from freeze-drying and post-freeze-drying storage stresses. Active cultures of the w...
ORGANISM(S): Lactobacillus Paracasei 
PXD043736 |
UnknownNoncoding RNAs in gastric cancer: Research progress and prospects.
Not available
S-EPMC4970485 | biostudies-literature
UnknownHepatic DsbA-L protects mice from diet-induced hepatosteatosis and insulin resistance.
Not available
S-EPMC5434661 | biostudies-literature
UnknownThe Effects of Disinfection Byproduct 2,6-Dichloro-1,4-benzoquinone on the Cyanobacterium <i>Microcystis aeruginosa</i>: From the Perspectives of Biochemistry and Non-Targeted Metabolomics.
Not available
S-EPMC11768523 | biostudies-literature
MetabolomicsMetabolomic Profiling of the Striatum in Shank3 Knockout ASD Rats: Effects of Early Swimming Regulation

OBJECTIVE: This study aimed to investigate the regulatory impact of early swimming intervention on striatal metabolism in Shank3 gene knockout ASD model rats.

METHODS: Shank3 gene knockout exon 11-21 male 8-day-old SD rats were used as experimental subject...

2024-09-27 | MTBLS8577 | MetaboLights
TranscriptomicsIdentification of latent tuberculosis infection-related microRNAs in human U937 macrophages expressing Mycobacterium tuberculosis Hsp16.3
Latent tuberculosis infection (LTBI) relies on a homeostasis of macrophages and Mycobacterium tuberculosis (Mtb). The small heat shock protein, Mtb Hsp16.3 (also known as latency-associated antigen), plays an important role in Mtb persistence within macrophages. However, the mechanism of LTBI remain...
ORGANISM(S): Homo sapiens 
2014-03-17 | E-GEOD-54630 | biostudies-arrayexpress
TranscriptomicsExpression data from MTDH knockdown in the Hec50co endometrial cancer cell line
Understanding the molecular underpinnings of chemoresistance is vital to design therapies to restore chemosensitivity. In particular, metadherin (MTDH) has been demonstrated to have a critical role in chemoresistance. Over-expression of MTDH has recently been implicated in poor clinical outcome in b...
ORGANISM(S): Homo sapiens 
2010-12-17 | E-GEOD-26134 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human tetracycline-regulated cell line expressing an NF-kB inhibitor to systematically identify NF-kB dependent genes
TNF time course series of HelA tet off cells cultured in presence or absence of Dox; TNF is a pro-inflammatory cytokine that controls expression of inflammatory genetic networks. Although the Nuclear Factor-kB (NF-kB) pathway is crucial for mediating cellular TNF responses, the complete spectrum of...
ORGANISM(S): Homo sapiens 
2007-09-07 | E-GEOD-2624 | biostudies-arrayexpress
Proteomicspseudomonas fluorescens LC-MSMS
our work revealed a rewired regulatory network of mqsA in P. fluoresces, in which a new transcription factor is recruited and incorporated to fulfill the similar physiological function.
ORGANISM(S): Pseudomonas fluorescens F113 
2019-01-30 | PXD008578 | Pride
Pseudomonas fluorescens lc-msms proteomics 
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