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Velvet antler is an organ composed of skin, nerves, blood vessels, cartilage and other tissues. Due to its ability to regenerate annually, it is used as a model for regeneration and medical research into cartilage related diseases. The study of the growth and development mechanisms of antlers has be...
ORGANISM(S): Elaphurus Davidianus 
Osteochondral defects (OCD) cannot be efficiently repaired due to the unique physical architecture and the pathological microenvironment including enhanced oxidative stress and inflammation. Conventional strategies, such as the control of implant microstructure or the introduction of growth factors,...
ORGANISM(S): Rattus Norvegicus Mus Musculus 
2022-03-04 | PXD031852 |
Reader proteins play significant roles in cell signaling from site-specific lysine methylation, but the progress of new reader investigations is rather slow. Photoreactive crosslinkers enable reader identifications, but it requires laborious chemical synthesis for optimization of the photoreactive g...
ORGANISM(S): Homo Sapiens 
2024-02-04 | PXD049149 |
The native microenvironment following osteochondral defect is not permissive for its endogenous regeneration. A variety of hydrogels have been developed to regulate cell behaviors; however, there is still a lack of hydrogels with multifunctional properties that can provide a supportive microenvironm...
ORGANISM(S): Rattus Rattus 
2021-11-28 | PXD030026 |
The hPDLSCs were cultured in the tenogenic medium treated with 0.1 ng/ml IL-1β or 10 ng/ml TNF-α for 7 days. Total proteins were isolated from the collected cell samples. Subsequently, the LFQ-based proteomic analysis was conducted for the extracted proteins in each group as established procedures...
ORGANISM(S): Homo Sapiens 
After treated with different stiffness and macrophage paracrine signals at the same stiffness for 3 days, MSCs were harvested for proteomic analysis. The label-free quantification (LFQ) based proteomic analysis was performed for global protein expressions.
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD035511 |
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