Sort   by:  
 Page size 
ProteomicsProteomic Profiling of Mycobacterium tuberculosis in Response to ILE Treatment
This study aims to elucidate the global proteomic changes in Mycobacterium tuberculosis upon treatment with the novel compound ilamycin E(ILE), which targets the Clp protease system. Label-free quantitative proteomics was employed to assess differential protein expression after ILE exposure. The res...
ORGANISM(S): Mycobacterium tuberculosis H37Ra 
2026-02-09 | PXD066355 | Pride
Mycobacterium tuberculosis Tuberculosis Ilamycin e 
ProteomicsHigh-fat diet alters retinal lipid composition and gene expression networks in mice
To reveal whether a long-term HFD alters gene expression levels in the retina, we used 4D-label free mass spectrometry to quantify proteins in the whole retinas of HFM and age-mated NM. As the liver plays a crucial role in metabolism of the whole body, HFD has a huge impact on gene expression in the...
ORGANISM(S): Mus Musculus 
PXD052242 |
MetabolomicsGNPS - HILIC LC-MS/MS of sputum from CF patients treated with tobramycin
LC-MS/MS HILIC Analysis. The methanol metabolite extracts from three patients for the oxygen experiments with Aspergillus reads (CF157, CF146 and CF353) and three without (CF178, CF243, CF69) were additionally used for the HILIC chromatography analysis to more efficiently detect tobramycin and its m...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-08-17 | MSV000081456 | GNPS
ProteomicsLISS enables immune evasion of colorectal cancers irrespective of MSI status
LISS enables immune evasion of colorectal cancers irrespective of MSI status
ORGANISM(S): Homo Sapiens 
PXD078805 |
ProteomicsDisruption of STIM1-mediated Ca2+ sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis and lean mass
STIM1 is a single-pass transmembrane endoplasmic/sarcoplasmic reticulum (E/SR) protein recognized for its role in store operated Ca2+ entry (SOCE), an ancient and ubiquitous signaling pathway. Whereas STIM1 is indispensable during development, its biological and metabolic functions in mature muscle ...
ORGANISM(S): Mus Musculus (mouse) 
2021-12-30 | PXD030674 | JPOST Repository
ProteomicsNuclear condensation of CDYL links histone crotonylation and cystogenesis in autosomal dominant polycystic kidney disease
We identify the Kcr sites on histones that are targeted by CDYL in ADPKD cells (WT9-12 cells). We chose to knock out CDYL in WT 9-12 cells (CDYL KO) through CRISPR/Cas9-mediated gene editing to increase the overall levels of histone Kcr. We quantified Kcr modifications on different histone residues ...
ORGANISM(S): Homo Sapiens 
2022-01-17 | PXD031029 |
ProteomicsER-associated degradation ligase HRD1 links ER stress to DNA damage repair by modulating the activity of DNA-PKcs
ER-associated degradation ligase HRD1 links ER stress to DNA damage repair by modulating the activity of DNA-PKcs
ORGANISM(S): Homo Sapiens 
PXD055020 |
ProteomicsGlobal phosphoproteomic analysis of mouse spermatocytes identified key kinases regulating meiosis
Protein phosphorylation, as one of the most important post-translational modifications, exerts crucial roles in regulating meiosis. However, there is a lack of systemic phosphoproteomic and functional analysis of phosphorylation in the meiosis of spermatocytes. To characterize the phosphorylation ev...
ORGANISM(S): Mus Musculus 
2022-03-07 | PXD032089 |
ProteomicsDDX39B K63-linked ubiquitination mediated by TRIM28 promotes NSCLC metastasis by enhancing ECAD lysosomal degradation
DDX39B interacted with E3 ubiquitin ligase TRIM28 and underwent TRIM28-mediated K63-linked ubiquitination at Lys241, Lys384, and Lys398, leading to DDX39B protein stabilization and upregulation.
ORGANISM(S): Homo Sapiens 
PXD064812 |
Sort   by:  
 Page size