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GenomicsRNA-seq analysis of human cells overexpressing a novel short XIST transcript isoform
RNA-seq analysis of human cells overexpressing a novel short XIST transcript isoform
PRJNA1336047 | ENA
ProteomicsHistone monoaminylation dynamics are regulated by a single enzyme and promote neural rhythmicity
Histone H3 monoaminylations at glutamine(Q) 5 represent an important family of epigenetic markers in neurons that play critical roles in the mediation of permissive gene expression (1, 2). We previously demonstrated that H3Q5 serotonylation(ser) and dopaminylation(dop) are catalyzed by the Transglut...
ORGANISM(S): Homo sapiens (Human) 
2024-10-10 | PXD053429 | Pride
Tgm2 Serotonylation Neural rhythmicity Histone h3 
UnknownChemoenzymatic synthesis of the sialyl Lewis X glycan and its derivatives.
Not available
S-EPMC2945603 | biostudies-literature
UnknownRinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells.
Not available
S-EPMC6716522 | biostudies-literature
ProteomicsKDM5-mediated transcriptional activation of ribosomal protein genes alters translation efficiency to regulate mitochondrial metabolism
Genes encoding the KDM5 family of transcriptional regulators are disrupted in individuals with intellectual disability (ID). To understand the link between KDM5 and ID, we generated five Drosophila strains harboring missense alleles analogous to those observed in patients. These alleles showed effec...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-11-14 | PXD046963 | Pride
Ribosome Neuron Kdm5 Brain Ipscs Translation Transcription Kdm5c Histone demethylase Ribo-seq 
TranscriptomicsEgr2-dependent expression in T cell anergy
T cell anergy is one of the mechanisms contributing to peripheral tolerance, particularly in the context of progressively growing tumors and in tolerogenic treatments promoting allograft acceptance. We recently reported that early growth response gene 2 (Egr2) is a critical transcription factor for...
ORGANISM(S): Mus musculus 
2013-04-21 | E-GEOD-46242 | biostudies-arrayexpress
UnknownA glycan-based approach to cell characterization and isolation: Hematopoiesis as a paradigm.
Not available
S-EPMC9455685 | biostudies-literature
UnknownDrosophila RpS12 controls translation, growth, and cell competition through Xrp1.
Not available
S-EPMC6936874 | biostudies-literature
ProteomicsComprehensive single cell transcriptomics analysis of murine osteosarcoma uncovers Skp2 function in metastasis, genomic instability and immune activation and reveals additional target pathways
Osteosarcoma (OS) is the most common primary pediatric bone malignancy. One promising new therapeutic target is SKP2, encoding a substrate recognition factor of the SCF E3 ubiquitin ligase responsible for ubiquitination and proteasome degradation of substrate p27, thus driving cellular proliferation...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-12 | PXD059605 | Pride
Osteosarcoma  skp2  single-cell rna-sequencing  tumor heterogeneity  immune infiltration  lineage plasticity 
UnknownInhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody.
Not available
S-EPMC2903239 | biostudies-literature
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