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TranscriptomicsRNA-seq analysis of C. elegans mina-1 mutants
Comparative transcriptomics study between C. elegans wild-type N2 and mina-1 mutants.
ORGANISM(S): Caenorhabditis elegans 
2019-02-13 | E-MTAB-7389 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of C. elegans CPEB homolog mutants.
Comparative transcriptomics study between C. elegans wild-type N2 and CPEB homolog mutants: fog-1, cpb-2, and cpb-3.
ORGANISM(S): Caenorhabditis elegans 
2017-08-03 | E-MTAB-4720 | biostudies-arrayexpress
MetabolomicsLsr2, a novel cyclic di-GMP receptor, regulate the synthesis of keto-mycolic acid and control biofilm formation in mycobacteria

Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
TranscriptomicsImpaired TLR3-mediated immune responses from macrophages of patients chronically infected with Hepatitis C virus
Hepatitis C virus (HCV) is the most common chronic blood-borne infection in the United States with the majority of patients becoming chronically infected and a subset (20%) progressing to cirrhosis and hepatocellular carcinoma. Individual variations in immune responses may help define successful res...
ORGANISM(S): Homo sapiens 
2013-03-05 | E-GEOD-40812 | biostudies-arrayexpress
TranscriptomicsWidespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions
We show that N6-methyladenosine (m6A), the most abundant internal modification in mRNA/lncRNA with still poorly characterized function, alters RNA structure to facilitate the access of RBM for heterogeneous nuclear ribonucleoprotein C (hnRNP C). We term this mechanism m6A-switch. Through combining P...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-56010 | biostudies-arrayexpress
ProteomicsProtemic analysis of the effect of c-di-GMP and c-di-AMP on the protein expression of Mycobacterium smegmatis
c-di-GMP and c-di-AMP are important conserved second messenger in bacteria, they play a critical role in a wide range of cellular processes, such as motility, virulence, biofilm formation, cell-cycle progression and cell development, but there are only two c-di-GMP receptors and one c-di-AMP recepto...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
2019-07-03 | PXD010623 | Pride
C-di-gmp Ittaq Mycobacterium smegmatis C-di-amp 
ProteomicsProteomic profiling and comparison of specific neurons in C. elegans
This work describes the results of using the MACSPI-SILAC method to profile and compare the proteome of dopaminergic neurons and touch receptor neurons in C. elegans.
ORGANISM(S): Caenorhabditis elegans 
2026-03-30 | PXD070040 | Pride
Proteomics Macspi C. elegans Dopaminergic neurons Lc-ms/ms Touch receptor neurons 
OtherWidespread Proteome Remodeling and Aggregation in Aging C. elegans.
Data from ProteomeXchange, PXD ID: PXD001364. Experiment: AggregatesSILAC_DAF16_D01, file: 20110921_Velos3_DiWa_SA_Celegans_AggregatesSILAC_DAF16_D01-3.mzml. Published as part of Cell. 2015 May 7;161(4):919-932 . From the Abstract: {{i}} ... Here, we profiled more than 5, 000 proteins along the lif...
ORGANISM(S): Worm, Escherichia_coli_k_12_substr__mg1655 
GPM32310019629 | GPMDB
Resource Reanalysis 
TranscriptomicsTranscription profiling by high throughput sequencing of 7 tissues of maize inbred line Zheng 58
RNA-sequencing of 5 tissues of maize inbred line Zheng 58: mature silk (MS), mature pollen (MP), mature ovary (MO), and 6-days old seedling (SL), immature silk (IMS)
ORGANISM(S): Zea mays 
2013-01-26 | E-MTAB-964 | biostudies-arrayexpress
MetabolomicsLipidOA: A Machine-Learning and Prior-Knowledge-Based Tool for Structural Annotation of Glycerophospholipids
The Paternò-Büchi (PB) reaction is a carbon-carbon double bond (C═C)-specific derivatization reaction that can be used to pinpoint the location(s) of C═C(s) in unsaturated lipids and quantitate the location of isomers when coupled with tandem mass spectrometry (MS/MS). As the data of PB-MS/MS are in...
2022-11-23 | MTBLS6075 | MetaboLights
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