Sort   by:  
 Page size 
ProteomicsSemaglutide targets mitochondria to regulate metabolism and inflammation in sarcopenia and osteoarthritis
Metabolic and inflammatory diseases often coexist, and become important challenges facing global health. As a traditional anti-obesity drug, semaglutide is reported to have therapeutic effects in sarcopenia and osteoarthritis (OA), but its mechanism of action still needs to be explored. Here we empl...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-06 | PXD073074 | Pride
C2c12 Semaglutide Mitochondria 
ProteomicsA single gene mutation underpins metabolic adaptation and acquisition of filamentous competence in the emerging fungal pathogen Candida auris
Filamentous cell growth is a vital property of fungal pathogens. The mechanisms of filamentation in the emerging multidrug-resistant fungal pathogen Candida auris are poorly understood. Here, we show that exposure of C. auris to glycerol triggers a rod-like filamentation-competent (RL-FC) phenotype,...
ORGANISM(S): Fungi [Candida] auris Candida 
2024-06-12 | PXD047167 | Pride
Candida auris Bcr1 Mcu1 Skin colonization Metabolic adaptation 
ProteomicsTandem Mass Tag based quantitative proteomic analysis of colorectal cancer cell lines
Overexpression of Oxysterol-Binding Protein-Related Protein 3 (ORP3) in colorectal cancer cell lines
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD074308 | Pride
ProteomicsBiotin-pgRNAWT or Biotin-pgRNAAUUUA to AUCUC RNA pulldown LC-MS/MS
The nuclear export of HBV RNAs allows the virus to synthesize its proteins through the translation machinery and replicate its genome through reverse transcription in the cytoplasm. However, the molecular mechanisms underlying this important process remain largely obscure. To illustrate this process...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD044015 | Pride
Rna nuclear export Pgrna binding proteins Rna stability Au rich element Hbv rna 
UnknownBaseline Functional Connectivity Features of Neural Network Nodes Can Predict Improvement After Sound Therapy Through Adjusted Narrow Band Noise in Tinnitus Patients.
Not available
S-EPMC6620714 | biostudies-literature
ProteomicsDIA proteomic profiling of dorsal skin from Dendrobium officinale polysaccharide-treated C57BL/6 mice
This project contains DIA-PASEF proteomics data generated from dorsal skin tissues of male C57BL/6 mice in a control group, a DHT-induced androgenetic alopecia (AGA) model group, and a Dendrobium officinale polysaccharide (DOP, 7.5 mg/mL)-treated group. The study was designed to investigate proteomi...
ORGANISM(S): Mus Musculus 
2026-04-20 | PXD077413 |
ProteomicsThe proteome data of extracellular vesicles derived from human umbilical cord and bone marrow mesenchymal stem cells
The protein samples stored at -80 °C were thawed and treated with lysis buffer (8M urea, 1% protease inhibitor, 50mM NH4HCO3) for 5 minutes in room temperature. After ultrasonic cracking on ice and centrifugation at 14000g for 10 min at 20 °C, the amount of total protein of each MSC sample was detec...
ORGANISM(S): Homo Sapiens 
2023-06-12 | PXD042977 |
ProteomicsThe proteome data of human mesenchymal stem cell derived from healthy donors
The protein samples stored at -80 °C were thawed and treated with lysis buffer (8M urea, 1% protease inhibitor, 50mM NH4HCO3) for 5 minutes in room temperature. After ultrasonic cracking on ice and centrifugation at 14000g for 10 min at 20 °C, the amount of total protein of each MSC sample was detec...
ORGANISM(S): Homo Sapiens 
2023-06-12 | PXD033812 |
ProteomicsSingle-cell transcriptome atlas reveals the underlying mechanism of kynurenic acid in regulation tumor immune microenvironment in glioblastoma
We performed 4D-DIA approach to quantified the proteome of GBM tissues from two groups. An average of 8880 quantified proteins were identified in each sample. In order to further explore the regulation of Kyna on GMB-resident T cells at the protein level, we performed 4D-DIA proteome analysis of CD4...
ORGANISM(S): Mus Musculus 
2025-10-30 | PXD070137 |
UnknownPrevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.
Not available
S-EPMC7880913 | biostudies-literature
Sort   by:  
 Page size