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Roxadustat (FG-4592) is a HIF-PHI for patients with low hemoglobin associated with chronic kidney disease. Due to the variety of HIF-mediated adaptive responses, FG-4592 has garnered growing therapeutic interest for use against various diseases, such as kidney and lung injury, obesity and related co...
ORGANISM(S): Homo sapiens (Human) 
2023-03-22 | PXD037002 | Pride
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights

Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights
Metabolic reprogramming is a critical driver in the pathogenesis of gastric cancer (GC). However, the intricate regulatory mechanisms that govern this reprogramming and their role in GC progression remain inadequately understood. Here, we have elucidated that Methyltransferase-like 10 (METTL10) is a...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD057247 | Pride
We performed LINP1 RNA pulldown followed by HPLC-MS analysis to identify LINP1-interacting proteins in A431 cells. With high performance liquid chromatography-mass spectrometry (HPLC-MS), the binding protein of LINP1 from RNA pull down was detected by removing non-specific protein which were binding...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD032027 | Pride
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