Sort   by:  
 Page size 
GenomicsCUT&RUN Targeting c-FOS, c-JUN and SOX2 in neurospheres derived from mouse brain cells
Other than in the development of the brain, SOX2 is essential for the long-term self-renewal of neural stem cells (NSCs). The mechanisms of how SOX2 maintains the stemness of NSCs is not yet understood. We have identified Fos as a downstream target of SOX2, and therefore used CUT&RUN to investigate ...
ORGANISM(S): Mus musculus 
2021-04-01 | E-MTAB-9897 | biostudies-arrayexpress
UnknownDouble strain-release enables formal C-O/C-F and C-N/C-F ring-opening metathesis.
Not available
S-EPMC11310891 | biostudies-literature
ProteomicsNanoproteomics analysis reveals single C. elegans heterogeneity during aging
Aging was long assumed to be a passive and stochastic process caused by random damage accumulation, however，such theories fail to explain the program-like features of the aging process. Measuring the aging process in C. elegans at individual level provides an opportunity to analyze both the programm...
ORGANISM(S): Caenorhabditis elegans 
2023-11-14 | PXD039330 | Pride
C. elegans Aging Lc-msms 
UnknownCorticosteroids significantly increase cystatin C levels in the plasma by promoting cystatin C production in rats.
Not available
S-EPMC6711078 | biostudies-literature
MetabolomicsGlycerol 3-phosphate phosphatase/PGPH-2 counters metabolic stress and promotes healthy aging via a glycogen sensing-AMPK-HLH-30-autophagy axis in C. elegans
Metabolic stress caused by excess nutrients accelerates aging. We recently demonstrated that the newly discovered enzyme glycerol-3-phosphate phosphatase (G3PP; gene Pgp), which operates an evolutionarily conserved glycerol shunt that hydrolyzes glucose-derived glycerol-3-phosphate to glycerol, coun...
2024-02-07 | MTBLS6847 | MetaboLights
ProteomicsThe chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans
In this study, a GFP-tagged version of the protein HCF-1 was immuno-precipitated from C. elegans lysates of the strain IU171 and co-purifying proteins were identified by LC-MS/MS. As a negative control, the same immuno-precipitation was conducted from wild-type (strain N2) worms that did not carry a...
ORGANISM(S): Caenorhabditis elegans 
2024-01-29 | PXD047509 | Pride
Lc-msms C. elegans Immuno precipitation 
ProteomicsProteome Analysis of Avian Metapneumovirus C Type infected Vero cells by iTRAQ coupled with LC-MS
To date, no study has been carried out to assess the protein profiles of aMPV/C-infected cells. In the present study, iTRAQ combined with LC-MS/MS was used to reveal the global proteomic changes occurring in Vero cells in response to aMPV/C infection for the first time and to help understand the mol...
ORGANISM(S): Cercopithecus aethiops (Green monkey) (Grivet) 
2020-04-03 | PXD017827 | Pride
Vero cells Lc-ms Ampv/c 
UnknownDual roles of c-Myc in the regulation of hTERT gene.
Not available
S-EPMC4176324 | biostudies-literature
TranscriptomicsMapping the C. elegans non-coding transcriptome with a whole genome tiling microarray
The number of annotated protein coding genes in the genome of Caenorhabditis elegans is similar to that of other animals, but the extent of its non-protein coding transcriptome remains unknown. Expression profiling on whole genome tiling microarrays applied to a mixed stage C. elegans population ver...
ORGANISM(S): Caenorhabditis elegans 
2007-09-06 | E-GEOD-8543 | biostudies-arrayexpress
TranscriptomicsGene expression and synergistic interactions induced by CpG ODN and/or poly(I:C)
Bioinformatic analysis of microarray data was used to identify the regulatory patterns underlying changes in gene expression induced when RAW 264.7 macrophages were stimulated via TLR9 by CpG oligonucleotides (ODN) and/or via TLR3 by poly (I:C). While the genes activated by each ligand mediated simi...
ORGANISM(S): Mus musculus 
2009-07-21 | E-GEOD-15416 | biostudies-arrayexpress
Sort   by:  
 Page size