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ProteomicsDifferential Proteomics of pprI-Knockout Deinococcus radiodurans: A Label-Free Quantitative Analysis
Deinococcus radiodurans, renowned for its exceptional resistance to radiation, provides a robust model for elucidating cellular stress responses and DNA repair mechanisms. The global regulator PprI plays a pivotal role in maintaining this resilience by coordinating DNA damage repair, antioxidant def...
ORGANISM(S): Deinococcus radiodurans 
2025-06-30 | PXD062500 | Pride
Radiation response metalloprotease  label-free quantitative proteomics  dna damage repair  antioxidant defense  metabolic regulation 
UnknownCircular RNA circ-LDLRAD3 as a biomarker in diagnosis of pancreatic cancer.
Not available
S-EPMC5743505 | biostudies-literature
MetabolomicsDistinct metabolic profiling is correlated with bisexual flowers formation resulting from exogenous ethephon induction in melon (Cucumis melo L.)

Melon (Cucumis melo L.) is an agronomically important vegetable. Most cultivars of melon are andromonoecious and bisexual flowers only emerged from the leaf axil of lateral branches. However, the regulatory mechanism contributing to the occurrence of bisexual flowers were still obscure. ...

2022-03-10 | MTBLS2993 | MetaboLights
ProteomicsSILAC based quantitative 3-hydroxybutyromics of HBO1-WT and HBO1-KO HeLa cells
Ketogenesis derived BHB facilitates 3-hydroxybutyrylation on lysine linking metabolism with epigenetic regulation. Herein, we found HBO1 served as 3-hydroxybutyryltransferase preferentially catalyzing lysine 9 of histone H3 (H3K9bhb). Moreover, total 1171 Kbhb sites on 582 proteins were identified. ...
ORGANISM(S): Homo sapiens (Human) 
2025-07-04 | PXD051668 | Pride
Human Cervical cancer Kbhb Hbo1 Lc-ms/ms 
ProteomicsLabel-free DDA proteome for identifying the interacting proteins of HBO1
HBO1 is an important transcriptional activator for organism to respond to natural stress. Here, we performed IP-MS for determining the interacting proteins of HBO1 under stimulation of BHB.
ORGANISM(S): Homo sapiens (Human) 
2025-07-04 | PXD051692 | Pride
Human Label-free Ip-ms Hbo1 
Proteomicslabel free quantitative proteomics for determining the biological characterastic of eukaryocyte with or without BHB.
BHB is the major part of ketone body in plasm that is usually at low concentration. Dramatical increase of BHB is due to prologation fasting or diabetes. In addation to enegetic carrier for metabolic reprogramming, BHB is also involved in epigenetic regulation. Here, we illustrats the BHB-induced pr...
ORGANISM(S): Homo sapiens (Human) 
2025-07-04 | PXD051685 | Pride
Human Bhb Label-free Lc-ms/ms 
ProteomicsIntegrative proteomics and precision N-glycoproteomics analyses of rheumatoid arthritis synovia reveal immune-associated glycopeptides
The precision glycoproteome in the synovium and its clinical significance are completely unknown. We performed precision N-glycoproteomics analysis of RA and OA synovial tissues, and identified many immune-associated N-glycopetides in this study for the first time, providing new insights into the me...
ORGANISM(S): Homo Sapiens 
2023-03-10 | PXD037581 |
ProteomicsAcellular Nerve Perineurium Repairs Peripheral Nerve Injuries in a Rat Model via ECM-Mediated Barrier and Optimization of the Regenerative Microenvironment: Raw date of the proteomics analysis in this study
The project IPX0014571000 in iProX as an example dataset, which is composed of the raw data and analysis results of the study paper"Acellular Nerve Perineurium Repairs Peripheral Nerve Injuries in a Rat Model via ECM-Mediated Barrier and Optimization of the Regenerative Microenvironment".
ORGANISM(S): Rattus Norvegicus Canis Lupus Familiaris 
2025-12-17 | PXD071986 |
UnknownIncidence and prevalence of asthma, chronic obstructive pulmonary disease and interstitial lung disease between 2004 and 2023: harmonised analyses of longitudinal cohorts across England, Wales, South-East Scotland and Northern Ireland.
Not available
S-EPMC12322415 | biostudies-literature
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