Association of Kidney Function With Risk of Adverse Effects of Therapies for Atrial Fibrillation.

ABSTRACT:

Introduction

Atrial fibrillation (AF) is common in chronic kidney disease (CKD) and is treated with rate control medications, antiarrhythmic medications, as well as anticoagulation and procedures, each of which have associated risks. We aimed to evaluate the association of CKD status with the risks of adverse effects after initiation of AF therapies.

Methods

This was a cohort study of community-based adults who newly initiated rate control medications, antiarrhythmic medications, warfarin, direct oral anticoagulants (DOACs) or received AF procedures in the 1 year after diagnosis of AF. Baseline estimated glomerular filtration rate (eGFR) was calculated using outpatient serum creatinine measures. Adverse effects within 1 year related to each AF therapy or within 1 month of an

SUBMITTER: Bansal N 

PROVIDER: S-EPMC10014389 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature