Exploring the role of gut microbiota in autoimmune thyroid disorders: a systematic review and meta-analysis.

ABSTRACT:

Background

Autoimmune thyroid diseases (AITDs) are characterized by unique immune responses against thyroid antigens and persist over time. The most common types of AITDs are Graves' disease (GD) and Hashimoto's thyroiditis (HT). There is mounting evidence that changes in the microbiota may play a role in the onset and development of AITDs.

Objective

The purpose of this comprehensive literature study was to answer the following query: Is there a difference in microbiota in those who have AITDs?

Methods

According to the standards set out by the PRISMA statement, 16 studies met the requirements for inclusion after being screened for eligibility.

Results

The Simpson index was the only diversity measure shown to be considerably lower in patients with GD c

SUBMITTER: Alkader DAA 

PROVIDER: S-EPMC10641821 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature