Application of ¹⁸F-NaF-PET/CT in assessing age-related changes in the cervical spine.

ABSTRACT:

Background

Cervical spondylosis is the degeneration of cervical spine often associated with aging and neck pain. As the degenerative changes are coupled with altered osteoblastic activity, imaging modalities sensitive to such molecular changes could be valuable for clinical assessment, disease prophylaxis, and monitoring early therapy response. In this study, we examined the role of ¹⁸F-sodium fluoride-positron emission tomography/computed tomography (¹⁸F-NaF-PET/CT) in detecting age-associated changes in the cervical spine of an adult population with broad age spectrum.

Methods

In this retrospective cross-sectional study, we analyzed ¹⁸F-NaF-PET/CT scans of 88 control volunteers (43 females, 45 males) with age ranging from 21 to 75 years (me

SUBMITTER: Park PSU 

PROVIDER: S-EPMC9131326 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature