Value of pre-treatment ¹⁸F-FDG PET/CT radiomics in predicting the prognosis of stage III-IV colorectal cancer.

ABSTRACT:

Background and purpose

To investigate the value of radiomics features extracted from pre-treatment ¹⁸F-FDG PET/CT in predicting the outcomes of stage III-IV colorectal cancer (CRC), which may assist in clinical management strategies and precise treatment of stage III-IV CRC.

Materials and methods

124 patients with pathologically confirmed stage III-IV CRC who underwent pre-treatment ¹⁸F-FDG PET/CT scans were enrolled in this study. The least absolute shrinkage and selection operator Cox regression (LASSO-Cox) was used to select radiomics features, and the radiomics scores (Rad-scores) were calculated to build radiomics models. The performance of radiomics models was represented by the concordance index (C-index) and compared with clinical models and com

SUBMITTER: Wang N 

PROVIDER: S-EPMC9941411 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature