Sort   by:  
 Page size 
ProteomicsCollagen-derived prolyl-hydroxyproline dipeptide promotes cellular homeostasis and lamellipodia-driven cell motility through active β1-integrin in adult tendon cells
Collagen-derived hydroxyproline-containing peptides show a variety of biological properties in cells. However, no comprehensive study has yet explored the functional links between Hyp-containing peptides and cellular behavior. Here, we show that the dipeptide prolyl-hydroxyproline (Pro–Hyp) exhibits...
ORGANISM(S): Mus musculus (Mouse) 
2022-09-28 | PXD020374 | Pride
Collagen-derived peptide  proline-hydroxyproline  adult tendon cells  extracellular matrix  scleraxis  cell motility  extracellular signal-regulated kinase 
ProteomicsThe dipeptide prolyl-hydroxyproline promotes cellular homeostasis and lamellipodia-driven motility via active ?1-integrin in adult tendon cells
Collagen-derived hydroxyproline-containing peptides show a variety of biological properties in cells. However, no comprehensive study has yet explored the functional links between Hyp-containing peptides and cellular behavior. Here, we show that the dipeptide prolyl-hydroxyproline (Pro–Hyp) exhibits...
ORGANISM(S): Mus musculus (Mouse) 
2021-05-27 | PXD023176 | Pride
Collagen-derived peptide  proline-hydroxyproline  adult tendon cells  extracellular matrix  scleraxis  cell motility  extracellular signal-regulated kinase 
TranscriptomicsTranscription profiling of mouse developing and adult cornea compared to the lens and tendon
The cornea continues to mature after birth to develop a fully functional, refractive and protective barrier tissue. Here we investigated the complex biological events underlying this process by profiling global genome-wide gene expression patterns of the immature postnatal day 10 and seven week-old ...
ORGANISM(S): Mus musculus 
2008-10-21 | E-GEOD-11900 | biostudies-arrayexpress
ProteomicsProteomic analysis of scleraxis mutant tendon
Tendons play fundamental role in the musculoskeletal system and locomotion by transferring forces generated by muscles to the skeleton. Tendon injuries can occur due to sports related incidents, as a result of trauma to overuse or during disease or ageing and are among the leading causes of musculos...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD017944 | Pride
Scleraxis Tendon Lc-ms/ms 
TranscriptomicsTranscription profiling of mouse tendon, cornea, and skin fibroblasts stimulated with mechanical stress to test the hypothesis that fibroblasts from different tissues are phenotypically distinct from one another.
In order to test the hypothesis that fibroblasts from different tissues are phenotypically distinct from one another, we have subjected tendon, skin and corneal fibroblasts of fetal mouse to mechanical stimulation by fluid flow and analyzed the transcriptional responses of the cells using Affymetrix...
ORGANISM(S): Mus musculus 
2007-10-12 | E-GEOD-3486 | biostudies-arrayexpress
GenomicsGene expression profile at single cell level of Tendon at neonate or adult sample with or without injury
Gene expression profile at single cell level of Tendon at neonate or adult sample with or without injury
PRJNA1208955 | ENA
UnknownViable tendon neotissue from adult adipose-derived multipotent stromal cells.
Not available
S-EPMC10800559 | biostudies-literature
GenomicsRegenerative potential of neonatal tendon cells is regulated by intrinsic resistance to inflammation and supportive T cell-secreted factors
Regenerative potential of neonatal tendon cells is regulated by intrinsic resistance to inflammation and supportive T cell-secreted factors
PRJNA1232158 | ENA
UnknownScleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis.
Not available
S-EPMC7850622 | biostudies-literature
UnknownMohawk impedes angiofibrosis by preventing the differentiation of tendon stem/progenitor cells into myofibroblasts.
Not available
S-EPMC9678895 | biostudies-literature
Sort   by:  
 Page size