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OtherA proteomic ruler for protein copy number and concentration estimation without spike-in standards.
Data from ProteomeXchange, PXD ID: PXD000661. Experiment: A549, file: 20121023_EXQ4_JRW_SA_32L_3.mzml. Published as part of Mol Cell Proteomics. 2014 Sep 15 . From the Abstract: {{i}} ... Here we present a novel concept that delivers similar quantitative results directly from deep eukaryotic proteo...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320003525 | GPMDB
Resource Reanalysis 
OtherA proteomic ruler for protein copy number and concentration estimation without spike-in standards.
Data from ProteomeXchange, PXD ID: PXD000661. Experiment: TPA_Lung, file: 20120207_EXQ6_JRW_TPA_Lung_28_1_T.mzml. Published as part of Mol Cell Proteomics. 2014 Sep 15 . From the Abstract: {{i}} ... Here we present a novel concept that delivers similar quantitative results directly from deep eukary...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM11210029853 | GPMDB
Resource Reanalysis 
UnknownThree proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.
Not available
S-EPMC2715809 | biostudies-literature
ProteomicsGenetic and pharmacologic inhibition of Keap1 dampens the pro-fibrotic program in human hepatic stellate cells
The increasing prevalence of chronic liver diseases (CLDs) is a global health concern. CLDs can cause fibrosis, and there is an urgent need for antifibrotic agents. The primary driver of fibrogenesis, transforming growth factor beta 1 (TGF-β1), activates hepatic stellate cells (HSCs), which are resp...
ORGANISM(S): Homo sapiens (Human) 
2026-09-24 | PXD076470 | Pride
Ecm Fibrosis Liver Nrf2 Anti-fibrotic drugs Antioxidant response 
TranscriptomicsDNA Topoisomerase 1a Promotes RNA-directed DNA Methylation and Histone Lysine 9 Dimethylation at Transposable Elements in Arabidopsis [RNA-Seq]
RNA-directed DNA methylation (RdDM) is a transcriptional silencing mechanism mediated by small and long noncoding RNAs produced by the plant-specific RNA polymerases Pol IV and Pol V, respectively. Through a chemical genetics screen with a luciferase-based DNA methylation reporter, LUCL, we found th...
ORGANISM(S): Arabidopsis thaliana 
2014-07-08 | E-GEOD-50719 | biostudies-arrayexpress
TranscriptomicsDNA Topoisomerase 1M-NM-1 Promotes RNA-directed DNA Methylation and Histone Lysine 9 Dimethylation at Transposable Elements in Arabidopsis
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Arabidopsis thaliana 
2014-07-08 | E-GEOD-50720 | biostudies-arrayexpress
ProteomicsModeling of DNA methylation in cis reveals principles of chromatin folding in vivo in the absence of crosslinking and ligation
Mammalian chromosomes are folded into intricate hierarchies of interaction domains, within which topologically associating domains (TADs) and CTCF-associated loops partition the physical interactions between regulatory sequences. Current understanding of chromosome folding largely relies on chromoso...
ORGANISM(S): Mus musculus (Mouse) 
2019-06-03 | PXD013507 | Pride
Proteomic ruler Tads Chromosomal interactions Mouse embryonic stem cells Ctcf-associated loops Topologically associating domains Chromosome folding 
UnknownCryo-EM structure and functional analysis of the chromatin remodeler RSF.
Not available
S-EPMC11189100 | biostudies-literature
UnknownThe INO80 chromatin remodeller facilitates DNA damage bypass via postreplicative gap repair.
Not available
S-EPMC12624141 | biostudies-literature
ProteomicsIron deficiency causes aspartate-sensitive metabolic dysregulation in CD8+ T-cells
Iron is an irreplaceable co-factor for important enzyme systems, and iron deficiency is the most common micronutrient deficiency worldwide. How iron deprivation influences normal cellular function remains poorly characterised. Using activated CD8+ T-cells as a model for dividing cells we show iron r...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-24 | PXD047814 | Pride
Metabolism Epigenetics Alpha-ketoglutarate Cd8+ t-cell Tca cycle Oxphos Mitochondria Iron Aspartate 
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