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ProteomicsHuman serum N-linked intact glycopeptides LC-MS/MS
Large-scale identification of N-linked intact glycopeptides by liquid chromatography coupled tandem mass spectrometry (LC-MS/MS) in human serum is challenging due to the wide dynamic range of serum protein abundances, the lack of a complete serum N-Glycan database and the existence of non-specifical...
ORGANISM(S): Armoracia rusticana Homo sapiens (Human) Gallus gallus (Chicken) 
2020-04-21 | PXD015622 | Pride
N-linked intact glycopeptide Co-elution Spectral library search Human serum Isotopic distribution 
OtherIs label-free LC-MS/MS ready for biomarker discovery?
Data from ProteomeXchange, PXD ID: PXD002037. Experiment: 01, file: folder summary. Published as part of Proteomics Clin Appl. 2015 Feb 5 .
ORGANISM(S): Streptococcus_pyogenes_m1_gas, Streptococcus_pyogenes_manfredo 
GPM11210037526 | GPMDB
Resource Reanalysis 
ProteomicsMulti-level – Intact, Subunits, and Peptides – Characterization of Antibody-Based Therapeutics by a Single-Column LC-MS setup
A comprehensive characterization of biotherapeutics, mandated by regulatory authorities, require analyses of a protein drug at multiple structure levels. Such multi-level characterization can be performed by mass spectrometry (MS), with established conventional MS-based assays of product quality att...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2025-02-26 | PXD054948 | Pride
Subunits Intact Lc-ms Ead C4-column Peptides 
UnknownAnalytical Methods for Quantification and Identification of Intact Glucosinolates in Arabidopsis Roots Using LC-QqQ(LIT)-MS/MS.
Not available
S-EPMC7826904 | biostudies-literature
OtherA double-barrel LC-MS/MS system to quantify 96 interactomes per day.
Data from ProteomeXchange, PXD ID: PXD001695. File: 20140827_EXQ00_FaHo_SA_SWI3_03.mzml. Published as part of Mol Cell Proteomics. 2015 Apr 17 . From the Abstract: {{i}} ... Here we develop a high-throughput workflow capable of dealing with large numbers of low or medium complexity samples and spec...
ORGANISM(S): Yeast 
GPM11210038526 | GPMDB
Resource Reanalysis 
ProteomicsProteomic analysis of cellular soluble proteins from human bronchial smooth muscle cells by combining nondenaturing micro 2DE and quantitative LC-MS/MS: Preparation of more than 4000 native protein maps
Soluble proteins of human bronchial smooth muscle cells (HBSMC) were separated by nondenaturing micro 2DE and a 30 mm X 40 mm area of the CBB-stained slab gel (1.0 mm thick) was cut into 1.1 mm X 1.1 mm squares, then the proteins in the 972 gel pieces (squares) were applied to quantitative LC-MS/MS....
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-23 | MSV000080002 | MassIVE
UnknownAn antibody-free LC-MS/MS method for the quantification of intact insulin-like growth factors 1 and 2 in human plasma.
Not available
S-EPMC7943504 | biostudies-literature
UnknownComplementary LC-MS/MS-Based N-Glycan, N-Glycopeptide, and Intact N-Glycoprotein Profiling Reveals Unconventional Asn71-Glycosylation of Human Neutrophil Cathepsin G.
Not available
S-EPMC4598777 | biostudies-literature
ProteomicsIntact mass LC-MS analysis of Flu B HA1 and HA2 proteins
To determine the sequences of the Flu HA1 and HA2 proteins, we performed intact mass LC-MS analysis. By reducing disulfide bridges two peaks corresponding to the HA1 and HA2 components were detected. Mass profiles were obtained for both glycosylated and deglycosylated HA proteins.
ORGANISM(S): Influenza A virus (A/Aquatic bird/Hong Kong/M603/98(H11N1)) 
2025-05-06 | PXD046130 | Pride
Intact mass Ha2 Ha1 Flu b 
UnknownDifferential Quantitative Determination of Site-Specific Intact N-Glycopeptides in Serum Haptoglobin between Hepatocellular Carcinoma and Cirrhosis Using LC-EThcD-MS/MS.
Not available
S-EPMC6465142 | biostudies-literature
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