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ProteomicsSerial interactome capture of the human cell nucleus
Novel RNA-guided cellular functions are paralleled by an increasing number of RNA binding proteins (RBPs). We present “serial interactome capture” (serIC), a multiple purification procedure of UV-crosslinked poly(A)-RNA-protein complexes that enables global RBP detection with maximal specificity. We...
ORGANISM(S): Homo sapiens (Human) 
2016-03-31 | PXD003664 | Pride
Rna binding proteins  interactome capture  nuclear rna binding proteome 
ProteomicsSerial interactome capture of the human cell nucleus
Novel RNA-guided cellular functions are paralleled by an increasing number of RNA binding proteins (RBPs). We present “serial interactome capture” (serIC), a multiple purification procedure of UV-crosslinked poly(A)-RNA-protein complexes that enables global RBP detection with maximal specificity. We...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080265 | MassIVE
ProteomicsRNA interactome capture identifies key proteins for herpesviral gene expression
The primary mRNA sequence determines its secondary structure and the repertoire of interacting RNA binding proteins (RBPs). The resulting mRNA ribonucleoprotein complex (mRNP) then influences all stages of the life of an mRNA. Here, we determined the mRNP composition of individual Kaposi Sarcoma Her...
ORGANISM(S): Homo sapiens (Human) Human gammaherpesvirus 8 
2026-01-23 | PXD056253 | Pride
Kshv Au-rich sequences Srsf3 Rna-binding-proteins Rna interactome capture Rna stability Codon optimization Herpesviral gene expression Rbps Lytic transcripts Orf57 
TranscriptomicsPromoter capture-C of primary HepG2 cells
We employed a massively parallel, high resolution Capture-C based method to simultaneously characterize the genome-wide interactions of all human promoters in any cell type. We applied this approach to study the promoter interactome of HepG2 cells (3 biological replicates). We designed a custom Agil...
ORGANISM(S): Homo sapiens 
2019-03-20 | E-MTAB-7144 | biostudies-arrayexpress
GenomicsCapture Hi-C identifies the chromatin interactome of colorectal cancer risk loci
Multiple regulatory elements distant to their targets on the linear genome can influence the expression of a single gene through chromatin looping. Chromosome conformation capture implemented in Hi-C allows for genome-wide agnostic characterization of chromatin contacts. However, detection of functi...
EGAS00001001085 | EGA
GenomicsRNA interactome capture identifies key proteins for herpesviral gene expression
RNA interactome capture identifies key proteins for herpesviral gene expression
PRJNA1065267 | ENA
ProteomicsRNA interactome capture in Escherichia coli globally identifies RNA-binding proteins
RNA-binding proteins (RPBs) are deeply involved in many fundamental cellular processes in bacteria and are vital for their survival. Despite this, few studies have so far been dedicated to globally identifying bacterial RBPs. We have adapted the RNA interactome capture (RIC) technique, originally de...
ORGANISM(S): Escherichia coli 
2023-03-30 | PXD032939 | Pride
Lc-ms Rna interactome capture Escherichia coli 
Genomicsena-DATASET-ICR-PTGT-05-02-2015-11:21:41:591-6 - samples
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci.
EGAD00001001243 | EGA
GenomicsRNA interactome capture in E. coli to identify RNA-binding proteins
RNA interactome capture in E. coli to identify RNA-binding proteins
PRJNA899553 | ENA
ProteomicsPhotoaffinity capture compounds to profile the Magic Spot Nucleotide interactomes
Magic Spot Nucleotides (MSN) regulate the stringent response, a highly conserved bacterial stress adaptation mechanism, enabling survival when confronted with adverse external challenges. In times of antibiotic crisis, a detailed understanding of the stringent response is of critical importance, as ...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium Escherichia coli 
2026-07-27 | PXD032009 | Pride
Chemical proteomics Magic spot nucleotides (msn) Stringent response 
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