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UnknownIntrinsic disorder drives N-terminal ubiquitination by Ube2w.
Not available
S-EPMC4270946 | biostudies-literature
GenomicsDisordered N-Terminal DNMT3A Domain Is Required for Mouse Postnatal Development
Disordered N-Terminal DNMT3A Domain Is Required for Mouse Postnatal Development
PRJNA689766 | ENA
UnknownN-terminal acetylation can stabilize proteins independent of their ubiquitination.
Not available
S-EPMC10067848 | biostudies-literature
ProteomicsATAD5-BAZ1B interaction modulates PCNA ubiquitination during DNA repair
Mono-ubiquitinated PCNA (mono-Ub-PCNA) is generated when replication forks stall and facilitates the DNA lesion bypass process. After resolving a replication stall, Ub-PCNA needs to be de-ubiquitinated to resume high-fidelity DNA synthesis. ATAD5 cooperates with UAF1-USP1 to de-ubiquitinate mono-Ub-...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD050108 | Pride
Baz1b De-ubiquitination Dna repair Usp1 Smarca5 Atad5 Baz1b Uaf1 Pcna 
ProteomicsStUbEx PLUS in U2OS
StUbEx PLUS – a modified Stable tagged Ubiquitin Exchange system for Peptide Level purification and in-depth mapping of Ubiquitination Sites. Applying StUbEx PLUS to U2OS cells treated with proteasomal inhibitors MG132 or Bortezomib resulted in the identification of 41,582 sites mapping on 7,762 pro...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD006092 | Pride
Site specific ubiquitination  ubiquitination sites  n-terminal ubiquitination  proteasomal inhibition  mg132: bortezomib 
ProteomicsThe identification of ubiquitination sites of IBTK by shotgun proteomics
Previous study reported that eIF4A1 protein stability is subject to control by the ubiquitin-proteasome pathway, and deubiquitinase USP9X elevated eIF4A1 protein level by promoting eIF4A1 deubiquitination. However, the E3 ubiquitin ligases responsible for eIF4A1 proteolysis is not determined. Our re...
ORGANISM(S): Homo sapiens (Human) 
2024-05-10 | PXD039031 | Pride
Ibtk Ubiquitination Shotgun 
UnknownUbiquitination of gasdermin D N-terminal domain directs its membrane translocation and pore formation during pyroptosis.
Not available
S-EPMC11914233 | biostudies-literature
UnknownPeripheral sequestration of huntingtin delays neuronal death and depends on N-terminal ubiquitination.
Not available
S-EPMC11330980 | biostudies-literature
TranscriptomicsDisordered N-Terminal DNMT3A Domain Is Required for Mouse Postnatal Development
DNA methyltransferase 3a (DNMT3A) plays a crucial role in multiple biological processes during mouse development. We report that the longer isoform DNMT3A1, but not the shorter DNMT3A2, is essential for mouse postnatal development. DNMT3A1 binds to and regulates bivalent developmental genes in the b...
ORGANISM(S): Mus musculus 
2022-03-21 | GSE164265 | GEO
UnknownGlucocorticoids differentially regulate degradation of MyoD and Id1 by N-terminal ubiquitination to promote muscle protein catabolism.
Not available
S-EPMC2265166 | biostudies-literature
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