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ProteomicsPhospho-proteomic Analyses Provide Insight into Underlying Molecular Mechanisms of NETosis
NETosis, a novel cell death leads to neutrophil extracellular trap (NET) formation, is involved in both infectious and noninfectious disease. However, mechanisms underlying NETosis remain unclear. To explore the underlying molecular mechanisms and common factors associated with both NOX-dependent an...
ORGANISM(S): Homo Sapiens 
2019-06-27 | PXD014418 |
ProteomicsTamm-Horsfall protein augments neutrophil NETosis
Proteome profiles of isolated peripheral human neutrophils pretreated with purified Tamm-Horsfall protein and stimulated to undergo NETosis with PMA.
ORGANISM(S): Homo sapiens (Human) 
2024-09-23 | PXD045468 | Pride
Netosis Urinary tract infection Tamm-horsfall protein Neutrophil 
UnknownRegulating NETosis: Increasing pH Promotes NADPH Oxidase-Dependent NETosis.
Not available
S-EPMC5816902 | biostudies-literature
GenomicsInhibition of netosis with PAD inhibitor attenuates endotoxin shock induced systemic inflammation
Inhibition of netosis with PAD inhibitor attenuates endotoxin shock induced systemic inflammation
PRJNA839858 | ENA
UnknownNETosis in pulmonary pleomorphic carcinoma.
Not available
S-EPMC11786310 | biostudies-literature
GenomicsInhibition of NETosis via PAD4 could alleviate the inflammation of giant cell myocarditis
Inhibition of NETosis via PAD4 could alleviate the inflammation of giant cell myocarditis
PRJNA912772 | ENA
UnknownTranscriptional firing helps to drive NETosis.
Not available
S-EPMC5296899 | biostudies-literature
ProteomicsCONNETTING ANTI-2GLYCOPROTEIN I ANTIBODIES, NETosis AND ENDOTHELIAL CELL ACTIVATION
This project aims to explore the intricate relationship between anti-β2glycoprotein I (aβ2GPI) antibodies, neutrophil extracellular traps (NETs), and endothelial cell activation in Antiphospholipid Syndrome (APS), an autoimmune disorder characterized by thrombotic events. This study tested the hypot...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD052010 | Pride
Netosis Autoimmune disorder Antiphospholipid syndrome Endothelial cell activation 
UnknownMachine Learning to Quantitate Neutrophil NETosis.
Not available
S-EPMC6858304 | biostudies-literature
ProteomicsNeutrophils from patients with recurring Panton-Valentine Leukocidin-positive Staphylococcus aureus infections are more sensitive to PVL induced NETosis
Panton-Valentine Leukocidin (PVL) is a Staphylococcus aureus toxin that binds to and kills human neutrophils resulting in the formation of neutrophil extracellular traps. A subset of individuals colonized with PVL expressing S. aureus suffer from recurring infections. We found that neutrophils from ...
ORGANISM(S): Homo sapiens (Human) 
2023-11-23 | PXD025702 | Pride
Netosis Nets Mrsa Leukocidin Staphylococcus aureus Pvl 
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