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The extracellular matrix is an important part of the cellular microenvironment regulating various cellular functions. Decellularized matrices present a valuable strategy for recreating the cellular niche in vitro and implementing matrix signaling in cell culture models. However, the tissue-specifici...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2020-03-23 | PXD014356 | Pride
The protein composition of porcine pancreatic tissue-derived decellularized extracellular matrix was identified.
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-01-27 | PXD047892 | Pride
Background: Members of E. coli serogroup O45 are porcine enteropathogenic E. coli (PEPEC) strains which cause post-weaning diarrhea and produce characteristic attaching and effacing (A/E) lesions. Most of O45 PEPEC strains possess the locus of enterocyte effacement (LEE), encoding the virulence fact...
ORGANISM(S): Escherichia coli 
The pancreatic endocrine cells, particularly the insulin secreting β-cells, adapt to pregnancy by increasing cell mass, size and altering secretory patterns. Since most studies utilize rodent models, translating findings to human pregnancy remains challenging. In this work, we performed an extensive...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-05-26 | PXD077246 | Pride
RNA-Seq analysis of porcine islets and pancreas to characterize the differentially expressed genes between higher and lower islet density
Primary human pancreatic ductal organoids (HPDO) have emerged as a model to study pancreas biology and model disease like pancreatitis and pancreatic cancer. Yet, donor material availability, genetic variability and a lack of extensive benchmarking to healthy and disease pancreas limits the range of...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2025-11-10 | PXD068063 | Pride
Gene expression patterns that form the basis for the observed variation in islet density among porcine pancreata were examined. RNA-Seq analysis was performed to investigate differential gene expression of intact porcine pancreas samples and pure cultured islet samples according to a density of isle...
ORGANISM(S): Sus scrofa 
2021-12-31 | GSE158226 | GEO
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