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UnknownImproved T Cell Surfaceomics by Depleting Intracellularly Labelled Dead Cells.
Not available
S-EPMC12859484 | biostudies-literature
UnknownImmunoproteomics and Surfaceomics of the Adult Tapeworm Hymenolepis diminuta.
Not available
S-EPMC6240649 | biostudies-literature
ProteomicsImproved T cell surfaceomics by depleting intracellularly labelled dead cells
Although the plasma membrane (PM) is among the most biologically important and therapeutically targeted cellular compartments, it is among the most challenging to faithfully capture using proteomic approaches. The quality of quantitative surfaceomics data depends heavily on the effectiveness of the ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD068422 | Pride
Glycosylation Intracellular pool Surfaceome Biotinylation Plasma membrane 
ProteomicsStructural surfaceomics of Nomo-1 using PhoX cross-linker with timsTOF
The project aimed to profile the cell surface proteins of Nomo-1 (AML cell line) using structural surfaceomics for identification of protein conformation-based cancer antigens thereby expanding the toolkit for cancer target discovery for immunotherapeutic targeting. To achieve the goal, cell surface...
ORGANISM(S): Homo sapiens (Human) 
2023-10-04 | PXD035591 | Pride
Xl-ms Phox Cell surfaceome Nomo-1 Aml 
ProteomicsStructural surfaceomics of Nomo-1 using DSSO cross-linker with MS3 approach
The project aimed to profile the cell surface proteins of Nomo-1 (AML cell line) using structural surfaceomics for identification of protein conformation-based cancer antigens thereby expanding the toolkit for cancer target discovery for immunotherapeutic targeting. To achieve the goal, cell surface...
ORGANISM(S): Homo sapiens (Human) 
2023-10-04 | PXD035589 | Pride
Ms3 Dsso Xl-ms Cell surfaceome Nomo-1 Aml 
ProteomicsStructural surfaceomics of myeloma models to identify tumor-specific protein conformations
Proteins at the cell surface are promising targets for cancer immunotherapies. While standard surface proteomics can be powerful for target discovery, even more fruitful is identifying cancer-specific surface protein features. To this end, we recently described a technology to identify cancer-specif...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD059495 | Pride
Cell surface proteomics  xl-ms  crosslinking mass spectrometry  structural biology  protein structure 
UnknownStructural surfaceomics reveals an AML-specific conformation of integrin β<sub>2</sub> as a CAR T cellular therapy target.
Not available
S-EPMC10663162 | biostudies-literature
ProteomicsCD317-Positive Immune Stromal Cells in Human "Mesenchymal Stem Cell" Populations
Surfaceomics (plasma membrane located protein expression) achieved through mass spectrometry on isolated plasma membranes of immortalised MSC lines
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-04-29 | MSV000089336 | MassIVE
ProteomicsA magnetic bead-based workflow for sensitive and streamlined cell surface proteomics
Cell-surface proteins represent an important class of molecules for therapeutic targeting and defining cellular phenotypes. However, their enrichment and detection via mass spectrometry-based proteomics remains challenging due to low abundance, posttranslational modifications, hydrophobic regions, a...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-01-21 | PXD043678 | Pride
Lc-ms  mass spectrometry  surfaceomics  cell surface capture  n-glycopeptide enrichment  plasma membrane n-glycoprotein 
ProteomicsLow Density Lipoprotein Receptor Targeting Chimeras for Membrane Protein Degradation and Enhanced Drug Delivery
Antibody-based therapeutics encompass diverse modalities for targeting tumor cells, among which antibody-drug conjugates (ADCs) and extracellular targeted protein degradation (eTPD) specifically depend on efficient lysosomal trafficking for activity. However, many tumor antigens exhibit poor interna...
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD064642 | Pride
Antibody based degradation 
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