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ProteomicsTMTpro: Design and initial evaluation of a novel Proline-based isobaric 16-plex Tandem Mass Tag reagent set
The design and synthesis of a novel proline-reporter-based isobaric Tandem Mass Tag 16 tag set (TMTpro) was carried out and the data uploaded here is a comparison of the performance of the new TMTpro tags with the current commercially available dimethylpiperidine-reporter-based TMT10/11 reagents. Da...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) Rattus norvegicus (Rat) 
2019-11-25 | PXD014750 | Pride
Tmt Tmtpro 
UnknownTandem Mass Tag labelling quantitative acetylome analysis of differentially modified proteins during mycoparasitism of Clonostachys chloroleuca 67-1.
Not available
S-EPMC8599485 | biostudies-literature
ProteomicsAutomated sample preparation workflow for tandem mass tag-based proteomics
Although tandem mass tag (TMT)-based isobaric labeling has become a powerful technique for multiplexed protein quantitation, it has not been easy to automate the workflow for widespread adoption. This is because preparation of TMT labeled peptide samples involves multiple steps ranging from protein ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD040788 | Pride
Automation Tandem mass tags Proteomics 
ProteomicsIdentification of potential plasma biomarkers for abdominal aortic aneurysm using tandem mass tag quantitative proteomics
Plasma biomarkers that identify abdominal aortic aneurysm (AAA) rupture risk would greatly assist in stratifying patients with small aneurysms. Identification of such biomarkers has hitherto been unsuccessful over a range of studies using different methods. The present study used an alternative prot...
ORGANISM(S): Homo sapiens (Human) 
2018-10-22 | PXD011309 | Pride
Plasma proteomics  immunodepletion  tandem mass tags  tmt  abdominal aortic aneurysm  cardiovascular diseases 
ProteomicsMultiplexed complexome profiling using tandem mass tags
Complexome profiling is a rapidly spreading, powerful approach to gain insight into the nature of protein complexes. It identifies and quantifies protein complexes separated into multiple fractions of increasing molecular mass using mass spectrometry-based, label-free bottom-up proteomics. Complexom...
ORGANISM(S): Homo sapiens (Human) 
2021-08-20 | PXD023211 | Pride
Complexome profiling  multiplexed complexomics  tandem mass tags  protein complexes 
ProteomicsProteomic Analysis of Cerebrospinal Fluids from Chronic Fatigue Syndrome Patients with and without Co-existing Fibromyalgia
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and fibromyalgia have overlapping neurologic symptoms particularly disabling fatigue. This has given rise to the question whether they are distinct central nervous system (CNS) entities or is one an extension of the other. To investigate th...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-09 | MSV000090685 | MassIVE
ProteomicsA Tandem Mass Tag (TMT) proteomic analysis during the early phase of experimental pancreatitis
We performed in a rat pancreatitic model a quantitative shotgun proteomic profiling of the soluble and whole membrane fractions from the pancreas during the early phase of cerulein (Cer)-induced AP compared to controls. Three control and three pancreatitic samples from both the soluble and the whole...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-05-22 | PXD007096 | Pride
Cerulein Rat pancreas Subcellular fractions Acute pancreatitis Tmt (tandem mass tags) 
ProteomicsEvosep One Enables Robust Quantitative Deep Proteome Coverage using Tandem Mass Tags while Significantly Reducing Machine Time
The balance between comprehensively analyzing the proteome and using valuable mass spectrometry time is a genuine challenge in the field of proteomics. Multidimensional fractionation strategies have significantly increased proteome coverage, but often at the cost of increased mass analysis time, des...
ORGANISM(S): Homo sapiens (Human) 
2019-04-04 | PXD012520 | Pride
Evosep Nonsmall cell lung carcinoma (nsclc) patient-derived xenografts (pdx) Tmt Mass analysis time Lc-ms/ms 
ProteomicsTandem Mass Tag proteomics in CHCHD10 patient cells
Mutations in CHCHD10, coding for a mitochondrial intermembrane space protein, are a rare cause of autosomal dominant amyotrophic lateral sclerosis (ALS). Mutation-specific toxic gain of function or haploinsuffuciency models have been proposed to explain pathogenicity. To decipher the metabolic dysfu...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD018806 | Pride
Human Fibroblasts Galactose Mitochondria 
ProteomicsTandem mass tag-based proteomic analysis in saliva of horses with acute abdominal disease
The objective of the study was to analyze the changes in proteomics that occur in saliva in acute abdominal disease (AAD) by proteomics in order to identify new proteins that could allow gaining knowledge about the physiopathological changes that can occur in this fluid and identify possible new bio...
ORGANISM(S): Equus caballus (Horse) 
2021-05-24 | PXD025241 | Pride
Proteomics Tmt Horse Saliva Acute abdominal disease 
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