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ProteomicsTarget identification for 11q13 amplicon
Proteomic strategy to define therapeutically relevant targets in cell lines that contain the 11q13 amplicon compared to those that do not and to ascertain which genes are amplified at the protein level and, concomitantly, are key drivers for tumor growth and/or maintenance. Furthermore, so called p...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000080001 | MassIVE
ProteomicsTarget identification for 11q13 amplicon
Proteomic strategy to define therapeutically relevant targets in cell lines that contain the 11q13 amplicon compared to those that do not and to ascertain which genes are amplified at the protein level and, concomitantly, are key drivers for tumor growth and/or maintenance. Furthermore, so called p...
ORGANISM(S): Homo sapiens (Human) 
2015-08-04 | PXD002486 | Pride
Human Lc-msms Head and neck Cell surface protein enrichment Breast 11q13 Liver Oscc Tmt6 quantitation 
TranscriptomicsCharacterization of amplification patterns and target genes at chromosome 11q13 in CCND1-amplified sporadic and familial breast tumors
Amplification of chromosomal region 11q13, containing the cell cycle regulatory gene CCND1, is frequently found in breast cancer and other malignancies. It is associated with the favourable oestrogen receptor (ER) positive breast tumour phenotype, but also with poor prognosis and treatment failure. ...
ORGANISM(S): Homo sapiens 
2011-11-23 | E-GEOD-32578 | biostudies-arrayexpress
TranscriptomicsOvarian Cancer CGH
OBJECTIVES: Amplification of the 11q13 locus is commonly observed in a number of human cancers including both breast and ovarian cancer. Cyclin D1 and EMS1 have been implicated as candidate oncogenes involved in the emergence of amplification at this locus. Detailed analysis of the 11q13 amplicon in...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-16408 | biostudies-arrayexpress
UnknownChromosome 11q13 deletion syndrome.
Not available
S-EPMC5177688 | biostudies-literature
UnknownTwo independent prostate cancer risk-associated Loci at 11q13.
Not available
S-EPMC2802212 | biostudies-literature
GenomicsCharacterization of amplification patterns and target genes at chromosome 11q13 in CCND1-amplified sporadic and familial breast tumors
Amplification of chromosomal region 11q13, containing the cell cycle regulatory gene CCND1, is frequently found in breast cancer and other malignancies. It is associated with the favourable oestrogen receptor (ER) positive breast tumour phenotype, but also with poor prognosis and treatment failure. ...
ORGANISM(S): Homo sapiens 
2011-11-23 | GSE32578 | GEO
UnknownPrognosis and Failure Patterns of 11q13 Amplified Local Advanced Squamous Cell Carcinoma of the Head and Neck.
Not available
S-EPMC12449658 | biostudies-literature
UnknownFrequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers.
Not available
S-EPMC1626089 | biostudies-literature
TranscriptomicsChromosome 11q and its association with CCND1 gene amplification and tamoxifen resistance in premenopausal breast cancer
Background: The amplification event occurring at chromosome locus 11q13, reported in several different cancers, includes a number of potential oncogenes. We have previously reported amplification of one such oncogene, CCND1, to be correlated with an adverse effect of tamoxifen in premenopausal breas...
ORGANISM(S): Homo sapiens 
2008-10-07 | E-GEOD-12759 | biostudies-arrayexpress
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