14-3-3 adaptor proteins

Show results for

Transcriptomics (374)
Genomics (143)
Unknown (58)
Proteomics (38)
Other (2)
Models (1)
Metabolomics (1)

Organisms

Mus musculus (260)
Homo sapiens (102)
Drosophila melanogaster (26)
Saccharomyces cerevisiae (19)
Arabidopsis thaliana (13)
Caenorhabditis elegans (10)
Danio rerio (8)
Trypanosoma brucei (6)
Salmonella enterica subsp. enterica serovar Typhimurium (4)
Oncorhynchus mykiss (3)
Gallus gallus (3)
Candida albicans (3)
Tetrahymena thermophila (2)
Dictyostelium discoideum (2)
Plasmodium berghei (2)
Lepidium sativum (2)
Schizosaccharomyces pombe (2)
Oryza sativa (2)
Rattus norvegicus (2)
Salmo trutta (1)
Beauveria bassiana (1)
Cordyceps militaris (1)
Streptomyces griseus (1)
Cunninghamia lanceolata (1)
Roseburia inulinivorans DSM 16841 (1)
Solanum chacoense (1)
Vitis riparia (1)
Vanderwaltozyma polyspora (1)
Leishmania infantum (1)
Ixodes scapularis (1)

Organisms

Mus musculus (5)
Homo sapiens (3)
Drosophila melanogaster (1)

Repository

biostudies-arrayexpress (507)
pride (27)
MassIVE (9)
ENA (9)
geo (4)
GPMDB (2)
jPOST (2)
BioModels (1)
MetaboLights (1)

Tissue

Cell culture (9)
Leaf (4)
B cell (3)
Macrophage (3)
Blood cell (2)
Cell suspension culture (2)
Diploid cell (2)
Plant cell (2)
Adipose tissue (1)
Blood (1)
Brain (1)
Cardiac muscle cell (1)
Early embryonic cell (1)
Embryo (1)
Embryonic stem cell (1)
Fibroblast (1)
Lymph node (1)
Photosynthetic cell (1)
Primary cell (1)

Disease

Normal (4)
Disease free (3)
Porphyria NOS (2)
Neuroblastoma (2)
Not Available (2)
Hepatomegaly (1)
Rett syndrome (1)
Embryonic lethal at day 8.5 to 9.5 (1)
Chronic granulomatous disease (1)
Infected with Drechmeria coniospora (1)
Malignant fibrous histiocytoma (1)
IRAK-4 Q293X mutation (1)
Not infected (1)
Chronic myeloid leukemia (1)
S enteritidis (1)
Acute leukemia (1)
Familial hypercholesterolemia (1)
Lymphoma (1)

Technology Type

Mass Spectrometry (27)
Shotgun proteomics (11)
Affinity purification coupled with mass spectrometry proteomics (9)
Data-dependent acquisition (6)
Bottom-up proteomics (5)
Mass spectrometry (1)
All-ion fragmentation (1)
SWATH MS (1)

Instrument Platform

NextSeq 500 (13)
Illumina NovaSeq 6000 (12)
Axon GenePix 4000B scanning hardware (8)
Illumina HiSeq 4000 (7)
Illumina HiSeq 2500 (6)
Illumina HiSeq 2000 (4)
Scanning hardware (3)
Illumina MiSeq (3)
Agilent G2565BA (2)
Axon- GenePix4000B (2)
ScanArray Express HT [PerkinElmer] (2)
ScanArray 4000XL [PerkinElmer] (2)
ScanArray Express HT (2)
Illumina Genome Analyzer II (2)
Vortex (2)
NextSeq 2000 (2)
Thermocycler; SPRI magnetic bead rack; Qubit fluorometer; Agilent Bioanalyzer (1)
Branson Digital Sonifier; refrigerated benchtop centrifuge; rotator; magnetic rack (1)
Controlled-environment growth chambers (long-day and short-day) (1)
Dissection tools; liquid nitrogen; −80 °C freezer (1)
Covaris sonicator, PCR thermocycler, magnetic rack for SPRI bead clean-up (1)
Liquid-nitrogen mortar and pestle, benchtop microcentrifuge, vortex mixer (1)
Dissecting tools, liquid nitrogen, −80 °C freezer (1)
Controlled-environment growth chamber (short-day; 8 h light / 16 h dark) (1)
Microcentrifuge (1)
Beadarray reader (1)
VersArray ChipReader [Bio-Rad Laboratories] (1)
Axon 4000B scanner (1)
ScanArray 4000 [PerkinElmer] (1)
428 [Affymetrix] (1)

Publication Date

2010 (66)
2014 (62)
2013 (59)
2015 (58)
2012 (47)
2016 (41)
2011 (37)
2008 (28)
2009 (19)
2007 (19)
2006 (15)
2021 (14)
2024 (11)
2025 (10)
2023 (10)
2022 (10)
2020 (10)
2005 (10)
2026 (7)
2019 (4)
2018 (3)
2017 (3)
2004 (2)
2003 (1)

UNIPROT ID/AC

P01308 (1)
P00533 (1)
P01133 (1)

Metabolite Name

PppGpp (1)
PA(14:0/6 keto-PGF1alpha) (1)
PA(i-12:0/PGF1alpha) (1)
PGP(22:6-OH/i-12:0) (1)
8-Anilino-5-(4-anilino-5-sulfonaphthalen-1-yl)naphthalene-1-sulfonic acid (1)
Leptosine (1)
PG(20:3-2OH/20:1) (1)
Cer(d20:1/PGE2) (1)
PG(18:3/PGJ2) (1)
Baloxavir marboxil (1)
Pentadeca-3,6,9-trienedioylcarnitine (1)
Cryptophycin 52 (1)
PE(18:4/20:5-OH) (1)
PC(22:6-2OH(7S, 17S)/DiMe) (1)
DG(18:3/22:1/0:0)[iso2] (1)
PE-NMe(22:6/18:4) (1)
1,2-Diphenyl-4-(2''-phenylsulfinethyl)-3,5-pyrazolidinedione (1)
1-Azidosulfanylnonane (1)
3-Methylthiophene (1)
MG(0:0/20:3/0:0) (1)
DG(18:1-2OH/a-17:0/0:0) (1)
3'-N-Acetylneuraminyl-N-acetyllactosamine (1)
TG(22:6/15:0/O-18:0) (1)
SEPHAROSE (1)
PA(20:5-3OH/10:0) (1)
Tetrac (1)
PA(20:5-OH/i-12:0) (1)
Trifluoroacetyl-l-lysyl-l-alaninanilide (1)
DG(i-12:0/PGE2/0:0) (1)
Perfluorophenanthrene (1)

IsPrivate

False (1)

First Public Date

2025 (3)
2026 (2)
2024 (1)
2023 (1)
2022 (1)
2019 (1)

Modelling Approach

Ordinary differential equation model (1)

Study type

Transcription profiling by array (155)
ChIP-seq (120)
RNA-seq of coding RNA (100)
RNA-seq of non coding RNA (31)
ChIP-chip by array (19)
Other (14)
Methylation profiling by high throughput sequencing (11)
ChIP-chip by tiling array (10)
Comparative genomic hybridization by array (10)
Animal - High-throughput sequencing (5)
Unknown experiment type (4)
Hi-C (4)
DNA-seq (3)
Transcription profiling by SAGE (2)
High-throughput sequencing (2)
Cell line - High-throughput sequencing (2)
Ribo-seq (2)
RNA-seq of coding RNA from single cells (2)
PRO-seq (1)
GRO-seq (1)
Differential (1)
Transcription profiling by tiling array (1)
RNAi profiling by array (1)
Bisulfite-seq (1)
ATAC-seq (1)
Methylation profiling by array (1)

Release Date

2010 (70)
2014 (64)
2013 (64)
2015 (61)
2012 (52)
2016 (41)
2011 (37)
2008 (28)
2009 (21)
2007 (20)
2021 (17)
2006 (15)
2023 (11)
2020 (11)
2022 (10)
2005 (10)
2024 (7)
2019 (5)
2018 (5)
2017 (5)
2025 (4)
2026 (3)
2004 (2)
2003 (2)

Lab affiliation

Associate Professor, Department of Biology, Massachusetts Institute of Technology and Whitehead Institute of Biomedical Research (3)
Faculty of Chemistry and Center for Synthetic Microbiology (SYNMIKRO) Head of the Core-Facility for Mass Spectrometry Marburg University Hans-Meerwein-Str. 4 35032 Marburg GERMANY (2)
1.Semmelweis University, Department of Pharmacology and Pharmacotherapy, Budapest, Hungary. 2.Pharmahungary Group, Szeged, Hungary (1)
Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany (1)
Center of High-throughput Biology, Dept. of Biochemistry and Molecular Biology, UBC (1)
Centre de recherche du Centre Hospitalier Universitaire (CHU) de Quebec-Université Laval, Québec, QC, Canada Centre de recherche sur le cancer de l’Université Laval, Québec, QC, Canada PROTEO-Quebec Network for Research on Protein Function, Engineering, and Applications, Québec, QC, Canada Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Québec, QC, Canada (1)
Chair of Biochemistry II, Theodor Boveri-Institute, Biocenter, University of Würzburg, Würzburg, Germany (1)
Cornell University, Plant Biology section (1)
Department of Biochemistry and Molecular Biology Graduate School and Faculty of Medicine, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan (1)
Department of Developmental Molecular and Chemical Biology Tufts University School of Medicine Boston MA (1)
Department of Genome Sciences University of Washington 3720 15th Ave NE Seattle WA 98195 (USA) (1)
Department of Genome Sciences, University of Washington, Seattle, WA, USA (1)
Department of Medicine II, Hematology/Oncology, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany (1)
Department of Plant Pathology, Entomology, and Microbiology Iowa State University (1)
Dept. of Developmental Molecular and Chemical Biology Tufts University School of Medicine Boston MA (1)
KU Leuven, Department of Cellular and Molecular Medicine, Laboratory of Peroxisome Biology and Intracellular Communication, 3000 Leuven, Belgium. (1)
Max-Planck-Institut für Molekulare Pflanzenphysiologie Wisenschaftspark Golm Am Mühlenberg 1 14476 Potsdam, Germany (1)
Protein Chemistry and Metabolism Unit St Vincent's Institute of Medical Research (SVI) 9 Princes Street Fitzroy, Victoria 3065 Australia (1)
Proteome Dynamics, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Str. 10, D-13092 Berlin, Germany Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany (1)
School of Integrative Plant Science Plant Biology Section Cornell University (1)
State Key Laboratory of Pharmaceutical Biotechnology, Jiangsu Key Laboratory of Molecular Medicine, Chemistry and Biomedicine Innovation Center, Medical School of Nanjing University, Nanjing 210093, China. (1)
Technical University of Munich, Chair of Proteomics and Bioanalytics, Emil-Erlenmeyer-Forum 5, 85354 Freising, Germany (1)
University of Missouri (1)
Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University (1)

Previous page
1 / 62
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 62
Next page

Sort by:

Relevance

Page size

Polypharmacological perturbation of the 14-3-3 adaptor protein interactome stimulates neurite outgrowth

Targeting protein-protein interactions (PPIs) is a promising, but under-exploited, approach in the development of drugs for many indications. 14-3-3 proteins are a family of adaptor molecules with ubiquitous and critical functions in dozens of cell signaling networks. 14-3-3s bind to hundreds of ‘cl...

ORGANISM(S): Rattus norvegicus (Rat)

2020-03-31 | PXD017317 | Pride

CaMKK2 Inactivation by cAMP-PKA Signaling and 14-3-3 Adaptor Proteins

The calcium-calmodulin (Ca2+-CaM) dependent protein kinase kinase-2 (CaMKK2) is activated by increases in intracellular Ca2+ and is a key regulator of cellular and wholebody energy metabolism. CaMKK2 inhibition protects against prostate cancer, hepatocellular carcinoma and metabolic derangements ind...

ORGANISM(S): Homo sapiens (Human)

2020-11-06 | PXD020133 | Pride

Cyclic amp (camp) Calcium-calmodulin (ca2+-cam) dependent protein kinase kinase-2 (camkk2) Protein kinase a (pka) 14-3-3 adaptor proteins

Role of 14-3-3ζ in the adipogenesis program and the differentiation of healthy adipose tissue

Obesity is an independent risk factor for diabetes and cardiovascular disease. Before effective anti-obesity therapies can be developed, understanding of what governs the production of healthy versus unhealthy fat tissue is required, as not all types confer equal risk. Adipogenesis requires the prec...

ORGANISM(S): Mus musculus (Mouse)

2022-03-01 | PXD001215 | Pride

14-3-3 Adipogenesis Adipocytes Differentiation Molecular adaptors

Binding of 14-3-3 reader proteins to phosphorylated DNMT1 facilitates aberrant DNA methylation and gene expression

Mammalian DNA (cytosine-5) methyltransferase 1 (DNMT1) is essential for maintenance methylation. Phosphorylation of Ser143 (pSer143) stabilizes DNMT1 during DNA replication. Here, we show 14-3-3 is a reader protein of DNMT1pSer143. In mammalian cells 14-3-3 colocalizes and binds DNMT1pSer143 post-DN...

ORGANISM(S): Mus musculus

2015-09-10 | E-GEOD-72860 | biostudies-arrayexpress

14-3-3 signal adaptor and scaffold proteins mediate GPCR trafficking.

Not available

S-EPMC6673703 | biostudies-literature

Structural insights into the functional roles of 14-3-3 proteins.

Not available

S-EPMC9523730 | biostudies-literature

CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins.

Not available

S-EPMC7705300 | biostudies-literature

14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination.