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ProteomicsDeregulated Expression of the 14q32 miRNA Cluster in Clear Cell Renal Cell Carcinomas
Clear cell renal cell carcinomas (ccRCC) are characterized by arm-wide chromosomal alterations. Loss at 14q is associated with disease aggressiveness in ccRCC, which responds poorly to chemotherapeutics. The 14q locus contains one of the largest miRNA clusters in the human genome; however, little is...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD036428 | Pride
Lpa Dia Q-tof Claudin-1 14q32 Iron Dnmt1 Timstof pro Ccrcc Atxn2 
TranscriptomicsGlobal Profiling in Vestibular Schwannomas Shows Critical Deregulation of MicroRNAs and Upregulation in those included in Chromosomal Region 14q32
Background: Vestibular Schwannomas are benign tumors that arise from Schwann cells in the VIII cranial pair and usually present NF2 gene mutations and/or loss of heterozygosity on chromosome 22q. Deregulation has also been found in several genes, such as ERBB2 and NRG1. MicroRNAs are non-coding RNAs...
ORGANISM(S): Homo sapiens 
2014-03-24 | E-GEOD-43571 | biostudies-arrayexpress
GenomicsAffymetrix SNP array data for acute leukemias with a 14q32/BCL11B rearrangement
Affymetrix SNP array data for acute leukemias with a 14q32/BCL11B rearrangement
PRJNA680304 | ENA
UnknownEssential Role of the 14q32 Encoded miRNAs in Endocrine Tumors.
Not available
S-EPMC8151414 | biostudies-literature
UnknownmiRMap: Profiling 14q32 microRNA Expression and DNA Methylation Throughout the Human Vasculature.
Not available
S-EPMC6694280 | biostudies-literature
GenomicsLoss of imprinting at the CTCF binding sites in the DLK1-DIO3 domain reactivates microRNA expression in acute promyelocytic leukaemia
We report the DNA-methylation profiling of 10 regions selected from the DLK1-DIO3 domain on chromosome 14q32 in BM/PB samples from patients with acute promyelocytic leukaemia (APL), other subclasses of acute myeloid leukaemia and healthy donors, using high-throughput amplicon bisulfite sequencing wi...
ORGANISM(S): Homo sapiens 
2014-02-13 | E-GEOD-42543 | biostudies-arrayexpress
TranscriptomicsModulation of gene expression after inducing expression of 14q32 miRNAs by CRISPR activation technology in lung adenocarcinoma
Most lung adenocarcinoma deaths are related to metastases, indicating the necessity of detecting and inhibiting tumor cell dissemination. We have identified that overexpression of miRNAs located on 14q32 was associated with metastasis in lung adenocarcinoma patients. For functional analysis, we util...
ORGANISM(S): Homo sapiens 
2018-03-12 | GSE99050 | GEO
UnknownDeregulated expression of the 14q32 miRNA cluster in clear cell renal cancer cells.
Not available
S-EPMC10150008 | biostudies-literature
UnknownInhibition of Mef2a Enhances Neovascularization via Post-transcriptional Regulation of 14q32 MicroRNAs miR-329 and miR-494.
Not available
S-EPMC5415962 | biostudies-literature
UnknownPosttranscriptional Regulation of 14q32 MicroRNAs by the CIRBP and HADHB during Vascular Regeneration after Ischemia.
Not available
S-EPMC6350214 | biostudies-literature
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