Sort   by:  
 Page size 
ProteomicsOff-target profiling of Olaparib using Thermal Proteome Profiling
Explore off-targets of Olaparib using 2D Thermal Proteome Profiling (2D-TPP)
ORGANISM(S): Homo sapiens (Human) 
2024-05-13 | PXD046614 | Pride
Thermal proteome profiling Parp 2d-tpp Olaparib 
ProteomicsOff-target profiling of Niraparib and Olaparib using Thermal Proteome Profiling
Explore off-targets of Niraparib and Olaparib using 2D Thermal Proteome Profiling (2D-TPP)
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD044334 | Pride
Thermal proteome profiling Parp Niraparib 2d-tpp Olaparib 
ProteomicsCross-Platform Chemoproteomics: Orbitrap-TMT vs timsTOF-diaPASEF
Chemoproteomics relies on precise and comprehensive quantification of protein–compound interactions, yet methodological comparisons across mass spectrometry platforms remain scarce. Here, we systematically benchmark tandem mass tag data-dependent acquisition (TMT-DDA) on an Orbitrap against label-fr...
ORGANISM(S): Homo sapiens (Human) 
2026-09-21 | PXD065032 | Pride
Dia Tmt Chemoproteomics Timstof Orbitrap Lc-msms 
Proteomics16-plex isobaric mass tags enable streamlined proteomics-based drug mechanism-of-action studies
Multiplexed quantitative proteomics enables the development of complex workflows for studying the mechanisms by which small molecule drugs interact with the proteome such as thermal proteome profiling (TPP) or multiplexed proteome dynamics profiling (mPDP). TPP measures changes in protein thermal st...
ORGANISM(S): Homo sapiens (Human) 
2021-02-25 | PXD020829 | Pride
Tmtpro Isobaric labeling 2d-tpp Tmt Mpdp Tpp 
Proteomics16-plex isobaric mass tags enable streamlined proteomics-based drug mechanism-of-action studies
Multiplexed quantitative proteomics enables the development of complex workflows for studying the mechanisms by which small molecule drugs interact with the proteome such as thermal proteome profiling (TPP) or multiplexed proteome dynamics profiling (mPDP). TPP measures changes in protein thermal st...
ORGANISM(S): Homo sapiens (Human) 
2021-02-25 | PXD020827 | Pride
Tmtpro Isobaric labeling 2d-tpp Tmt Mpdp Tpp 
Proteomics16-plex isobaric mass tags enable streamlined proteomics-based drug mechanism-of-action studies
Multiplexed quantitative proteomics enables the development of complex workflows for studying the mechanisms by which small molecule drugs interact with the proteome such as thermal proteome profiling (TPP) or multiplexed proteome dynamics profiling (mPDP). TPP measures changes in protein thermal st...
ORGANISM(S): Homo sapiens (Human) 
2021-02-25 | PXD020831 | Pride
Tmtpro Isobaric labeling 2d-tpp Tmt Mpdp Tpp 
Proteomics16-plex isobaric mass tags enable streamlined proteomics-based drug mechanism-of-action studies
Multiplexed quantitative proteomics enables the development of complex workflows for studying the mechanisms by which small molecule drugs interact with the proteome such as thermal proteome profiling (TPP) or multiplexed proteome dynamics profiling (mPDP). TPP measures changes in protein thermal st...
ORGANISM(S): Homo sapiens (Human) 
2021-02-25 | PXD020830 | Pride
Tmtpro Isobaric labeling 2d-tpp Tmt Mpdp Tpp 
Proteomics16-plex isobaric mass tags enable streamlined proteomics-based drug mechanism-of-action studies
Multiplexed quantitative proteomics enables the development of complex workflows for studying the mechanisms by which small molecule drugs interact with the proteome such as thermal proteome profiling (TPP) or multiplexed proteome dynamics profiling (mPDP). TPP measures changes in protein thermal st...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2021-02-25 | PXD020848 | Pride
Tmtpro Isobaric labeling 2d-tpp Tmt Mpdp Tpp 
Proteomics16-plex isobaric mass tags enable streamlined proteomics-based drug mechanism-of-action studies
Multiplexed quantitative proteomics enables the development of complex workflows for studying the mechanisms by which small molecule drugs interact with the proteome such as thermal proteome profiling (TPP) or multiplexed proteome dynamics profiling (mPDP). TPP measures changes in protein thermal st...
ORGANISM(S): Homo sapiens (Human) 
2021-02-25 | PXD020828 | Pride
Tmtpro Isobaric labeling 2d-tpp Tmt Mpdp Tpp 
ProteomicsNew antiviral small molecule inhibitors disturb interactions between cellular HSP70 and virus proteins
RNA virus outbreaks such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), Ebola virus (EBOV) and Zika virus (ZIKV) causing worldwide health emergencies have highlighted the urgent need of new antiviral strategies. Upon outbreaks with new, unmet viruses where knowledge of virus biology...
ORGANISM(S): Homo sapiens (Human) Filoviridae Ebolavirus 
2021-01-04 | PXD021494 | Pride
Antiviral compound 2d-tpp Virus proteins Tpp Lc-msms 
Sort   by:  
 Page size