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UnknownSkeletal FGFR1 signaling is necessary for regulation of serum phosphate level by FGF23 and normal life span.
Not available
S-EPMC8379418 | biostudies-literature
TranscriptomicsIncomplete X-inactivation initiated by a hypomorphic Xist allele in the mouse
Mammals have evolved a mechanism to compensate for the difference in the number of X chromosome genes between XX females and XY males by inactivating one of the two X chromosomes in females. This X chromosome inactivation phenomenon is triggered by Xist gene, which is essential for X-inactivation to...
ORGANISM(S): Mus musculus 
2011-03-30 | E-GEOD-27373 | biostudies-arrayexpress
TranscriptomicsRNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryo
Cloning mammals by somatic cell nuclear transfer (SCNT) is highly inefficient. Most SCNT-generated embryos die after implantation because of unidentified, complex epigenetic errors in the process of postimplantation embryonic development. Here, we identified the most upstream level of dysfunction le...
ORGANISM(S): Mus musculus 
2011-11-17 | E-GEOD-33208 | biostudies-arrayexpress
TranscriptomicsImpeding Xist expression from the active X chromosome improves mouse somatic cell cloning
Cloning mammals by somatic cell nuclear transfer (SCNT) is highly inefficient because of aberrant genomic reprogramming. In addition to random reprogramming errors, we hypothesized the presence of specific errors as evidenced by common anomalies among clones. We found that Xist, which normally inact...
ORGANISM(S): Mus musculus 
2010-09-16 | E-GEOD-23181 | biostudies-arrayexpress
UnknownOsteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis.
Not available
S-EPMC9691688 | biostudies-literature
UnknownDecreased Abundance of Genus Slackia in Individuals With Obesity and Colorectal Adenoma.
Not available
S-EPMC11330935 | biostudies-literature
ProteomicsPhosphoproteomics of Matrigel-embedded samples
Phosphoproteomics data of Matrigel-embedded HCT116 spheroid, and patient-derived colorecral cancer organoid
ORGANISM(S): Homo Sapiens (human) 
2019-02-24 | PXD009032 | JPOST Repository
TranscriptomicsEffect of maple syrup extract on the liver of mice fed a high-fat diet
The effects of the administration of maple syrup extract (MSX) on hepatic gene expression were investigated in mice fed high-fat diet. Male C57BL/6J mice aged 3 weeks were purchased from Charles River Japan (Kanagawa, Japan) and housed in a room maintained at 23 ± 1°C and 49 ± 16% humidity with a 12...
ORGANISM(S): Mus musculus 
2015-04-30 | E-GEOD-65667 | biostudies-arrayexpress
TranscriptomicsEffects of Morus alba L. (Mulberry) Leaf Extract in Hypercholesterolemic Mice on Suppression of Cholesterol Synthesis
To investigate effects of intake of mulberry leaf extracts on hypercholesterolemia, we performed gene expression profiling on rat liver by microarray analysis. Microarray analysis revealed that mulberry leaf extracts up-regulated the gene expression involved in suppression of cholesterol synthesis a...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-65839 | biostudies-arrayexpress
ProteomicsPRM of UMR106 pY-IP
UMR106 cells were untreated or treated with 5 mM Pi or 100 ng/ml FGF2 for 15 min. The lysates were digested with trypsin, and tyrosine-phosphorylated peptides were enriched by anti-phosphotyrosine antibody. Several selected peptides including FGFR1 with phosphorylated tyrosine residues were measured...
ORGANISM(S): Rattus Rattus (black Rat) 
2019-05-05 | PXD010791 | JPOST Repository
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