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MetabolomicsThe alpha-1A adrenergic receptor agonist A61603 reduces cardiac polyunsaturated fatty acid-Serum raw data
Not available
ORGANISM(S): Mus musculus 
ST000452 | MetabolomicsWorkbench
MetabolomicsThe alpha-1A adrenergic receptor agonist A61603 reduces cardiac polyunsaturated fatty acid-Heart raw data
Not available
ORGANISM(S): Mus musculus 
ST000451 | MetabolomicsWorkbench
ProteomicsProteomic analysis of the survival effect of TPO receptor agonist Romiplostim treatment in mice exposed to a lethal dose of radiation
Background: The thrombopoietin receptor agonist romiplostim (RP) is a therapeutic agent for immune thrombocytopenia that can achieve complete survival in mice exposed to a lethal dose of ionizing radiation. The estimated mechanism of the radio-protective/mitigative effects of RP has been proposed; h...
ORGANISM(S): Mus Musculus (mouse) 
2021-05-12 | PXD025921 | JPOST Repository
ProteomicsEffects of HIT and B2 agonist Terbutaline on muscle
Effects of high intensity training and the B2 agonist Terbutaline on muscle
ORGANISM(S): Homo sapiens (Human) 
2017-12-06 | PXD005480 | Pride
Shotgun proteomics Terbutaline Beta-2 agonist Sports doping Muscle 
TranscriptomicsTranscription profiling of mouse lung to study the effect of prostaglandin E receptor subtype EP3 on mouse asthma model.
We examined the effect of PGE receptor EP3 subtype on mouse OVA-induced asthma model. We treat EP3 agonist 3h after OVA challenge. After 24 h of 3rd OVA challenge, whole lung was isolated and the gene expression change was determined.
ORGANISM(S): Mus musculus 
2007-09-25 | E-GEOD-2276 | biostudies-arrayexpress
TranscriptomicsA Sphingosine 1-Phosphate 1 Receptor Agonist Modulates Brain Death-Induced Neurogenic Pulmonary Injury
Lung transplantation remains the only viable therapy for patients with end-stage lung disease; however, full utilization of this treatment strategy is severely compromised by the lack of donor lung availability. For example, the vast majority of donor lungs available for transplantation are obtained...
ORGANISM(S): Rattus norvegicus 
2010-07-30 | E-GEOD-22531 | biostudies-arrayexpress
ProteomicsSuperior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy
Polycystic ovary syndrome (PCOS) is a heterogeneous condition, of polyhedric pathogenesis and clinical presentation, defined by oligo-/anovulation, hyperandrogenism and/or polycystic ovaries. Metabolic complications are highly common also in patients suffering PCOS, including obesity, insulin resist...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-02 | PXD044134 | Pride
Pcos Glp1 Glp1/gip Glp1/gip/glucagon Glp1/e 
TranscriptomicsSustained Efficacy and Seroconversion with the Toll-Like Receptor 7 Agonist GS-9620 in the Woodchuck Model of Chronic Hepatitis B
Background & Aims: New therapies for chronic hepatitis B (CHB) are urgently needed since current treatments rarely lead to cure. We evaluated whether the oral small molecule toll-like receptor (TLR7) agonist GS-9620 could induce durable anti-viral efficacy in woodchucks chronically infected with woo...
ORGANISM(S): Marmota monax 
2015-04-16 | E-GEOD-67935 | biostudies-arrayexpress
ProteomicsAgonist-induced phosphorylation of orthologues of the orphan receptor GPR35 as an activation biomarker
Mass spectrometry, mutagenesis and labelling with [32P] orthophosphate identified that each of the five hydroxy-amino acids in the intracellular C-terminal tail of human GPR35a became phosphorylated in response to agonist occupancy of the receptor and that, apart from Ser294, each of these contribut...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD030548 | Pride
Gpcr 
ModelsLeBeau1999 - IP3-dependent intracellular calcium oscillations due to agonist stimulation from Cholecytokinin
The properties of inositol 1,4,5-trisphosphate (IP3)-dependent intracellular calcium oscillations in pancreatic acinar cells depend crucially on the agonist used to stimulate them. Acetylcholine or carbachol (CCh) cause high-frequency (10–12-s period) calcium oscillations that are superimposed on a ...
2024-09-02 | BIOMD0000000965 | BioModels
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